Thermo Scientific™

POROS™ CaptureSelect™ AAVX Affinity Resin

Catalog number: A36742
Thermo Scientific™

POROS™ CaptureSelect™ AAVX Affinity Resin

Catalog number: A36742
Catalog Number
Unit Size
250 mL
Price (USD)
Your Price:
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
A36742250 mL
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Product Overview
Citations & References
Additional Information
POROS CaptureSelect AAVX Affinity Resin is engineered to address the high selectivity and capacity requirements for large-scale downstream purification of a broad range of naturally occurring and synthetic adeno-associated virus (AAV) serotypes used for gene therapy applications. POROS CaptureSelect AAVX resin has demonstrated binding reactivity towards a set of AAV serotypes that includes AAV1 to AAV8, and AAVrh10 as well as synthetic serotypes.

Features of POROS CaptureSelect AAVX resin include:
• One-step AAV purification from crude material with high purity and yield
• High specificity and capacity, maximizing yield by significantly reducing process steps
• Superior capacity maintained at high flow rates
• Excellent scalability and easier handling and packing due to rigid polymeric bead
• Non-animal derived

POROS CaptureSelect AAVX Affinity Resin enables a robust, fast, and platformable purification process for wide-ranging AAV serotypes with excellent purity and yield obtained in one step. This resin comes with complete technical and regulatory support.

View other viral vector resins and supporting products ›

Main characteristics

Matrix: cross-linked poly(styrene-divinylbenzene) POROS beads
Average particle size: 50 µm
Ligand: CaptureSelect AAVX affinity ligand
Binding capacity: >1x1013 genome copies/mL of resin
Elution conditions: acidic elution with 0.1 M glycine, pH 3.0
Mechanical resistance: 100 bar (1,450 psi; 10 MPa)
Formulation buffer: 18% (v/v) ethanol

Free of animal components
CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).

For Research Use or Further Manufacturing. Not for use in diagnostic procedures.


Ligand Type
CaptureSelect AAVX affinity ligand
Particle Size
50 µm
250 mL
Product Line
Binding Capacity
>1x1013 genome copies/mL of resin
Shipping Condition
Wet Ice
Cross-linked poly(styrene-divinylbenzene) POROS beads
Column Type

Contents & Storage

Store in refrigerator at 2°C to 8°C.