Thermo Scientific™

POROS™ CaptureSelect™ AAVX Affinity Resin

Catalog number: A36744
Thermo Scientific™

POROS™ CaptureSelect™ AAVX Affinity Resin

Catalog number: A36744
Catalog Number
A36744
Unit Size
5,000 mL
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50 mL
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6,810.00
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25 mL
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3,245.00
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10 mL
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1,544.00
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250 mL
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13,630.00
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10,000 mL
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1,000 mL
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A367445,000 mLContact Us ›***-
A3674150 mL
6,810.00
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A3674025 mL
3,245.00
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A3673910 mL
1,544.00
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A36742250 mL
13,630.00
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A3674510,000 mLContact Us ›***-
A367431,000 mLContact Us ›***-
Product Overview
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POROS CaptureSelect AAVX Affinity Resin is engineered to address the high selectivity and capacity requirements for large-scale downstream purification of a broad range of naturally occurring and synthetic adeno-associated virus (AAV) serotypes used for gene therapy applications. POROS CaptureSelect AAVX resin has demonstrated binding reactivity towards a set of AAV serotypes that includes AAV1 to AAV8, and AAVrh10 as well as synthetic serotypes.

Features of POROS CaptureSelect AAVX resin include:
• One-step AAV purification from crude material with high purity and yield
• High specificity and capacity, maximizing yield by significantly reducing process steps
• Superior capacity maintained at high flow rates
• Excellent scalability and easier handling and packing due to rigid polymeric bead
• Non-animal derived

POROS CaptureSelect AAVX Affinity Resin enables a robust, fast, and platformable purification process for wide-ranging AAV serotypes with excellent purity and yield obtained in one step. This resin comes with complete technical and regulatory support.

View other viral vector resins and supporting products ›

Main characteristics

Matrix: cross-linked poly(styrene-divinylbenzene) POROS beads
Average particle size: 50 µm
Ligand: CaptureSelect AAVX affinity ligand
Binding capacity: >1x1013 genome copies/mL of resin
Elution conditions: acidic elution with 0.1 M glycine, pH 3.0
Mechanical resistance: 100 bar (1,450 psi; 10 MPa)
Formulation buffer: 18% (v/v) ethanol

CaptureSelect affinity ligands are created using a proprietary technology based on camelid-derived single-domain antibody fragments. The ligand is a 13-kDa fragment that comprises the three complementarity determining regions (CDRs) that form the antigen-binding domain, efficiently produced by the yeast Saccharomyces cerevisiae in a production process free of animal components.

For Research Use or Further Manufacturing. Not for use in diagnostic procedures.

Specifications

Column Type
Affinity
Form
Liquid suspension
Product Line
POROS™
Product Type
Affinity Resin
Shipping Condition
Wet Ice
Particle Size
50 micron

Contents & Storage

Store in refrigerator at 2–8°C.

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