Thermo Scientific™

POROS™ AAVX RoboColumn

Catalog number: A37795
Thermo Scientific™

POROS™ AAVX RoboColumn

Catalog number: A37795
Catalog Number
A37795
Unit Size
600 µL
Price (USD)
Availability
-
Quantity
Catalog Number
Unit Size
200 µL
Price (USD)
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
A37795600 µL
-
A37794200 µL
-
Product Overview
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RoboColumn chromatography products are small columns provided in 8-column strips. They are useful for fully automated and parallel chromatographic separations using robotic liquid handling platforms.

These RoboColumns are pre-packed with POROS CaptureSelect AAVX Affinity Resin (Cat. No. A36743), engineered to address the high selectivity and capacity requirements for downstream purification of a broad range of naturally occurring and synthetic adeno-associated virus (AAV) serotypes used for gene therapy applications. POROS CaptureSelect AAVX resin has demonstrated binding reactivity towards a set of AAV serotypes that includes AAV1 to AAV8 and AAVrh10, as well as synthetic serotypes.

POROS CaptureSelect AAVX resin enables a robust, fast, and platformable purification process for wide-ranging AAV serotypes with excellent purity and yield obtained in one step.

Features of POROS CaptureSelect AAVX resin include:

  • One-step AAV purification from crude material with high purity and yield
  • High specificity and capacity, maximizing yield by significantly reducing process steps
  • Superior capacity maintained at high flow rates
  • Excellent scalability and easier handling and packing due to rigid polymeric bead
  • Non-animal derived

Free of animal components

CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).

A wide selection of RoboColumns is available, including columns pre-packed with POROS ion exchange, HIC, and CaptureSelect affinity resins. All POROS high performance chromatography resins have a unique pore structure that provides excellent mass transport for high capacity and resolution over a wide range of flow rates.

RoboColumn is a registered trademark of Repligen Corporation.

WARNING: Cancer – www.P65Warnings.ca.gov

Specifications

For Use With
Robotic Liquid Handling
Particle Size
50 μm
Pore Size
100 nm
Stationary Phase
Immobilized CaptureSelect™ AAVX Ligand
Product Line
POROS CaptureSelect
Volume (Metric)
600 μL
Column Type
RoboColumn
Purification Target
AAV

Contents & Storage

Shipped in 18% ethanol. Store at 2°C to 8°C.

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