Alpha-Bungarotoxin Conjugates
Alpha-Bungarotoxin Conjugates
Invitrogen™

Alpha-Bungarotoxin Conjugates

Thermo Fisher Scientific ofrece una amplia selección de conjugados de alfa-bungarotoxina de Invitrogen, incluidos conjugados Alexa Flour y Alexa Flour Plus.
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Número de catálogoEtiqueta o tinte
B13422Alexa Fluor™ 488
B56130Alexa Fluor™ Plus 405
B35451Alexa Fluor™ 555
B13423Alexa Fluor™ 594
B35450Alexa Fluor™ 647
B1196Biotin-XX
T1175Tetrametilrodamina
B1601Sin marcar
Número de catálogo B13422
Precio (MXN)
-
Etiqueta o tinte:
Alexa Fluor™ 488

Thermo Fisher Scientific ofrece una amplia selección de conjugados de alfa-bungarotoxina de Invitrogen, incluidos conjugados Alexa Flour y Alexa Flour Plus. El alfa-bungarotoxina, un aminoácido péptido de 74 aminoácidos extraído del veneno de Bungarus multicinctus, se une con alta afinidad a la subunidad A del receptor nicotínico de acetilcolina (AChR) de las uniones neuromusculares.

Thermo Fisher Scientific ofrece una amplia selección de conjugados de alfa-bungarotoxina de Invitrogen, incluidos conjugados Alexa Fluor y Alexa Fluor Plus. El alfa-bungarotoxina, un aminoácido péptido de 74 aminoácidos extraído del veneno de Bungarus multicinctus, se une con alta afinidad a la subunidad A del receptor nicotínico de acetilcolina (AChR) de las uniones neuromusculares. Nuestra brillante y fotoestable Alexa Fluor 555 alfa-bungarotoxina es una opción superior de sonda para visualizar este receptor.

Los conjugados fluorescentes de alfa-bungarotoxina se pueden utilizar para facilitar la identificación de AChRs nicotínicos y la localización de uniones neuromusculares. La alfa-bungarotoxina conjugada se ha utilizado en diversas aplicaciones, como la inmunofluorescencia (IF), la inmunohistoquímica (IHC) y la citometría de flujo (FC).

For Research Use Only. Not for use in diagnostic procedures.
Especificaciones
Etiqueta o tinteAlexa Fluor™ 488
Tipo de productoConjugado
Subtipo de proteínaOtras proteínas
Cantidad500 μg
Condiciones de envíoTemperatura ambiente
Excitation/Emission495/519 nm
Línea de productosAlexa Fluor
Unit SizeEach
Contenido y almacenamiento
Almacenar en el congelador (de –5 °C a –30 °C) y proteger de la luz.

Citations & References (39)

Citations & References
Abstract
Precise localization of alpha7 nicotinic acetylcholine receptors on glutamatergic axon terminals in the rat ventral tegmental area.
Authors:Jones IW, Wonnacott S
Journal:J Neurosci
PubMed ID:15601930
'Alpha7 neuronal nicotinic acetylcholine receptors (nAChRs) constitute one of the predominant nAChR subtypes in the mammalian brain. Within the ventral tegmental area (VTA), nicotine application, paired with postsynaptic stimulation, contributes to a form of long-term potentiation, an effect attributed to presynaptic alpha7 nAChRs on glutamatergic afferents (Mansvelder and McGehee, 2000). ... More
Thyroid hormone controls the development of connections between the spinal cord and limbs during Xenopus laevis metamorphosis.
Authors:Marsh-Armstrong N, Cai L, Brown DD
Journal:Proc Natl Acad Sci U S A
PubMed ID:14691251
'During premetamorphic stages, Xenopus laevis tadpoles expressing either a dominant-negative thyroid hormone (TH) receptor or a type-III iodothyronine deiodinase transgene in the nervous system have reduced TH-induced proliferation in the spinal cord and produce fewer hindlimb-innervating motorneurons. During prometamorphic stages, innervation of the hindlimbs is reduced, and few functional neuromuscular ... More
Syncoilin, a novel member of the intermediate filament superfamily that interacts with alpha-dystrobrevin in skeletal muscle.
Authors:Newey SE, Howman EV, Ponting CP, Benson MA, Nawrotzki R, Loh NY, Davies KE, Blake DJ
Journal:J Biol Chem
PubMed ID:11053421
'Dystrophin coordinates the assembly of a complex of structural and signaling proteins that are required for normal muscle function. A key component of the dystrophin protein complex is alpha-dystrobrevin, a dystrophin-associated protein whose absence results in neuromuscular junction defects and muscular dystrophy. To gain further insights into the role of ... More
The dynamics of the rapsyn scaffolding protein at individual acetylcholine receptor clusters.
Authors:Bruneau E, Akaaboune M
Journal:J Biol Chem
PubMed ID:17283077
'Rapsyn, a cytoplasmic receptor-associated protein, is required for the clustering of acetylcholine receptors (AChRs). Although AChR dynamics have been extensively studied, little is known about the dynamics of rapsyn. Here, we used a rapsyn-green fluorescent protein (GFP) fusion protein and quantitative fluorescent imaging to study the dynamics of rapsyn in ... More
Carbofuran induces apoptosis of rat cortical neurons and down-regulates surface alpha7 subunit of acetylcholine receptors.
Authors:Kim SJ, Kim JE, Ko BH, Moon IS
Journal:Mol Cells
PubMed ID:15179037
'Carbofuran (CF), an anticholinesterase carbamate, is one of the most widely used N-methylcarbamate esters in insect and nematode control. Despite its serious adverse health effects on wildlife and humans, cellular and molecular studies of the damage of CF to CNS neurons are very limited. We have examined the cytotoxic effects ... More