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4-Bromo A-23187, Free Acid

Catalog number:  B1494

Invitrogen™  Related applications: Cell Viability, Proliferation & Function

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The Ca2+ ionophore 4-bromo A-23187 is commonly used for in situ calibrations of fluorescent Ca2+ indicators, to equilibrate intracellular and extracellular Ca2+ concentrations and to permit Mn2+ to enter the cell to quench intracellular dye fluorescence. Unlike A-23187, brominated A-23187 is essentially nonfluorescent and can be used with UV-excitable calcium indicators like fura-2, indo-1 and quin-2 as well as the visible light-excitable indicators, including fluo-4, fluo-3, Calcium Green and rhod-2. 4-bromo A-23187 can also be used to equilibrate extracelular and intrcellular Mg2+ concentrations, making it useful for calibrating Mg2+ indicators.
For Research Use Only. Not for use in diagnostic procedures.


Indicator Type: Ionophore
Product Size: 1 mg
Shipping Condition: Room Temperature

Contents & storage

Store in freezer (-5 to -30°C).


Manuals & protocols