Trimethyl borate, 99%, Thermo Scientific Chemicals
Trimethyl borate, 99%, Thermo Scientific Chemicals
Trimethyl borate, 99%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Trimethyl borate, 99%, Thermo Scientific Chemicals

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Catalog NumberQuantity
B20215.AK
also known as B20215-AK
250mL
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Catalog number B20215.AK
also known as B20215-AK
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Quantity:
250mL
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Chemical Identifiers
CAS121-43-7
IUPAC Nametrimethyl borate
Molecular FormulaC3H9BO3
InChI KeyWRECIMRULFAWHA-UHFFFAOYSA-N
SMILESCOB(OC)OC
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SpecificationsSpecification SheetSpecification Sheet
Assay (GC)≥98.5% (non-U.S. sourced material)
CommentMaterial sourced in the U.S. and in other countries
Assay from Supplier's CofA≥98.5% (U.S. sourced material)
Refractive Index1.3560-1.3590 @ 20°C (non-U.S. sourced material)
FormLiquid
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Trimethyl borate is a useful reagent in organic synthesis. It is involved in the production of resins, waxes and paints and acts as a methylation agent. As a boron source, it is used to prepare flame retardants, anti-oxidants and corrosion inhibitors. It reacts with Grignard reagents followed by hydrolysis to prepare boronic acid. It is also used as a precursor of borate esters, which finds application in Suzuki coupling reaction. It is an intermediate in the preparation of sodium borohydride.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trimethyl borate is a useful reagent in organic synthesis. It is involved in the production of resins, waxes and paints and acts as a methylation agent. As a boron source, it is used to prepare flame retardants, anti-oxidants and corrosion inhibitors. It reacts with Grignard reagents followed by hydrolysis to prepare boronic acid. It is also used as a precursor of borate esters, which finds application in Suzuki coupling reaction. It is an intermediate in the preparation of sodium borohydride.

Solubility
Miscible with tetrahydrofuran, ether, isoporpylamine, hexane and methanol.

Notes
Moisture sensitive. Keep container tightly closed in a dry and well-ventilated place. Incompatible with oxidizing agents. It decomposes slowly in the presence of moisture and rapidly in water.
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
RUO – Research Use Only
For an example of the low temperature reaction with Grignard reagents to give boronic acids., see: Org. Synth. Coll., 4, 68 (1963).

Bao, Z.; Zhang, W.; Cui, X.; Xu, J. Design, Optimization and Control of Extractive Distillation for the Separation of Trimethyl Borate-Methanol. Ind. Eng. Chem. Res. 2014, 53 (38), 14802-14814.

Chang, C. C.; Lee, K. Y.; Lee, H. Y.; Su, Y. H.; Her, L. J. Trimethyl borate and triphenyl borate as electrolyte additives for LiFePO4 cathode with enhanced high temperature performance. J. Power Sources 2012, 217, 524-529.