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Thermo Scientific Chemicals
4-Fluoro-2-(trifluoromethyl)benzonitrile, 98+%
CAS: 194853-86-6 | C8H3F4N | 189.11 g/mol
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Catalog number B20617.14
also known as B20617-14
Price (USD)
258.65
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Quantity:
25 g
Price (USD)
258.65
Online Exclusive
287.00Save 28.35 (10%)
Each
Chemical Identifiers
CAS194853-86-6
IUPAC Name4-fluoro-2-(trifluoromethyl)benzonitrile
Molecular FormulaC8H3F4N
InChI KeyLCCPQUYXMFXCAC-UHFFFAOYSA-N
SMILESFC1=CC=C(C#N)C(=C1)C(F)(F)F
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Specifications
Specification Sheet
Specification SheetFormLumps or fused solid
Melting Point (clear melt)43.0-49.0?C
Appearance (Color)White
Assay (GC)≥98.0%
It is used as a pharmaceutical intermediate. It is also used for the synthesis of diphenylthioethers.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is used as a pharmaceutical intermediate. It is also used for the synthesis of diphenylthioethers.
Solubility
Insoluble in water. Solubility in methanol is almost transparent.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
It is used as a pharmaceutical intermediate. It is also used for the synthesis of diphenylthioethers.
Solubility
Insoluble in water. Solubility in methanol is almost transparent.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only
General References:
- Jie Jack Li, et al. Rational Design and Synthesis of 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a Novel, Nonsteroidal Androgen Receptor Antagonist Devoid of Phototoxicity for Dermatological Indications.J. Med. Chem.,2008,51(21), 7010-7014.
- Lorna Mitchell, et al. 4-(Alkylthio)- and 4-(arylthio)-benzonitrile derivatives as androgen receptor antagonists for the topical suppression of sebum production.Bioorganic & Medicinal Chemistry Letters.2009,19(5), 1310-1313.