2-Amino-5-nitrophenol, 95%
2-Amino-5-nitrophenol, 95%
2-Amino-5-nitrophenol, 95%
Thermo Scientific Chemicals

2-Amino-5-nitrophenol, 95%

CAS: 121-88-0 | C6H6N2O3 | 154.125 g/mol
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Catalog number B20870.14
also known as B20870-14
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25 g
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Price (USD)
31.65
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35.00
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Each
Chemical Identifiers
CAS121-88-0
IUPAC Name2-amino-5-nitrophenol
Molecular FormulaC6H6N2O3
InChI KeyDOPJTDJKZNWLRB-UHFFFAOYSA-N
SMILESNC1=CC=C(C=C1O)[N+]([O-])=O
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SpecificationsSpecification SheetSpecification Sheet
FormCrystals or powder or crystalline powder
Appearance (Color)Orange-brown to brown
Assay (Non-aqueous acid-base Titration)≥94.0 to ≤106.0%
2-Amino-5-nitrophenol has been used as starting material in the synthesis of series of (Z)-2-(substituted aryl)-N-(3-oxo-4-(substituted carbamothioyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl) hydrazine carboxamides, as semi permanent (nonoxidative) hair colorant and as toner in permanent (oxidative) hair dye products, in synthesis of series of 7-benzylamino-2H-1,4-benzoxazin-3(4H)-ones, anticonvulsant agents. Also used as a reactant for, diazotation and coupling reactions, preparation of biologically and pharmacologically active molecules. It is also applied in hair dyes and to make azo dyes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Amino-5-nitrophenol has been used as starting material in the synthesis of series of (Z)-2-(substituted aryl)-N-(3-oxo-4-(substituted carbamothioyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl) hydrazine carboxamides, as semi permanent (nonoxidative) hair colorant and as toner in permanent (oxidative) hair dye products, in synthesis of series of 7-benzylamino-2H-1,4-benzoxazin-3(4H)-ones, anticonvulsant agents. Also used as a reactant for, diazotation and coupling reactions, preparation of biologically and pharmacologically active molecules. It is also applied in hair dyes and to make azo dyes.

Solubility
Insoluble in water. Solubility in methanol gives very faint turbidity. Soluble in alcohol, benzene, acetone, and diethyl ether.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only

General References:

  1. Christina L Burnett, et al. Final report on the safety assessment of amino nitrophenols as used in hair dyes.Int J Toxicol.,2009,28(6), 217S-251S .
  2. Nadeem Siddiqui, et al. Anticonvulsant and toxicity evaluation of newer 4H-benzo[1,4]oxazin-3-ones: The effect of two hydrogen bonding domains.Arch Pharm (Weinheim).,2010,343(11-12), 657-663.