Di-tert-butylchlorophosphine, 96%
Di-tert-butylchlorophosphine, 96%
Di-tert-butylchlorophosphine, 96%
Thermo Scientific Chemicals

Di-tert-butylchlorophosphine, 96%

CAS: 13716-10-4 | C8H18ClP | 180.656 g/mol
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5 g
25 g
Catalog number B20998.06
also known as B20998-06
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Ends: 30-Jun-2026
124.00
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Quantity:
5 g
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Price (USD)
105.65
Special offer
Online exclusive
Ends: 30-Jun-2026
124.00
Save 18.35 (15%)
Each
Chemical Identifiers
CAS13716-10-4
IUPAC Namedi-tert-butyl(chloro)phosphane
Molecular FormulaC8H18ClP
InChI KeyMCRSZLVSRGTMIH-UHFFFAOYSA-N
SMILESCC(C)(C)P(Cl)C(C)(C)C
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)Clear colorless to pale yellow
FormLiquid
Assay (GC)≥95.0%
Identification (FTIR)Conforms
Di-tert-butylchlorophosphine is associated with palladium(II) acetate and used in Suzuki-Miyaura cross-couplings of arylboronic acids with aryl bromides and chlorides. It serves as a ligand and used in the preparation of mono- and bidentate phosphine ligands in metal complexes for catalytic chiral asymmetric hydrogenations. Further, it is used in asymmetric and transition metal coupling reactions. In addition to this, it plays an important role in the preparation of other phosphines in catalytic polymerization reactions.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Di-tert-butylchlorophosphine is associated with palladium(II) acetate and used in Suzuki-Miyaura cross-couplings of arylboronic acids with aryl bromides and chlorides. It serves as a ligand and used in the preparation of mono- and bidentate phosphine ligands in metal complexes for catalytic chiral asymmetric hydrogenations. Further, it is used in asymmetric and transition metal coupling reactions. In addition to this, it plays an important role in the preparation of other phosphines in catalytic polymerization reactions.

Solubility
Miscible with terahydrofuran.

Notes
Air and moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents and strong reducing agents.
RUO – Research Use Only

General References:

  1. Brill, M.; Rominger, F.; Hofmann, P. 1,2-Bis(di-tert-butylphosphino)imidazole (dtbpi): A Versatile Imidazole-Based, Rigid, Bulky Bisphosphine Ligand for Transition Metals. Organometallics 2015, 34 (2), 506-521.
  2. Shih, W. C.; Ozerov, O. V. One-Pot Synthesis of 1,3-Bis(phosphinomethyl)arene PCP/PNP Pincer Ligands and Their Nickel Complexes. Organometallics 2015, 34 (18), 4591-4597.