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p-Tolyl chlorothionoformate, 97%
CAS: 937-63-3 | C8H7ClOS | 186.65 g/mol
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Catalog number B23501.18
also known as B23501-18
Price (USD)
248.65
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276.00Save 27.35 (10%)
Each
Quantity:
50 g
Price (USD)
248.65
Online Exclusive
276.00Save 27.35 (10%)
Each
Chemical Identifiers
CAS937-63-3
IUPAC Name4-methylphenyl chloromethanethioate
Molecular FormulaC8H7ClOS
InChI KeyUNCAXIZUVRKBMN-UHFFFAOYSA-N
SMILESCC1=CC=C(OC(Cl)=S)C=C1
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Specifications
Specification Sheet
Specification SheetIdentification (FTIR)Conforms
Appearance (Color)Clear yellow
FormLiquid
Refractive Index1.5700-1.5750 @ 20?C
Assay (GC)≥96.0%
p-Tolyl chlorothionoformate is used in dehydration reactions by cyclic elimination of thiocarbonate esters. It acts as a catalyst in the synthesis of alfa-L-2'-deoxythreofuranosyl nucleoside analogs and alkenes from hindered alcohols.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
p-Tolyl chlorothionoformate is used in dehydration reactions by cyclic elimination of thiocarbonate esters. It acts as a catalyst in the synthesis of alfa-L-2′-deoxythreofuranosyl nucleoside analogs and alkenes from hindered alcohols.
Solubility
Miscible with common organic solvents.
Notes
Store in cool place. Incompatible with strong oxidizing agents.
p-Tolyl chlorothionoformate is used in dehydration reactions by cyclic elimination of thiocarbonate esters. It acts as a catalyst in the synthesis of alfa-L-2′-deoxythreofuranosyl nucleoside analogs and alkenes from hindered alcohols.
Solubility
Miscible with common organic solvents.
Notes
Store in cool place. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- For examples of the use of aryl chlorothionoformates in dehydration reactions by cyclic elimination of thiocarbonate esters, see Phenyl chlorothionoformate, L00838.
- Toti, K. S.; Derudas, M.; McGuigan, C.; Balzarini, J.; Van Calenbergh, S. Synthesis and antiviral evaluation of alpha-l-2'-deoxythreofuranosyl nucleosides. Eur. J. Med. Chem. 2011, 46 (9), 3704-3713.
- Varaprasad, C. V.; Ramasamy, K. S.; Hong, Z. Synthesis of some monocyclic-N-acetyl 4'-aza-D-nucleosides. J. Heterocycl. Chem. 2006, 43 (2), 325-336.