Ethyl 2-butynoate is used as a precursor for the synthesis of 3-ethyl, 1-methyl 1-(2-nitrophenyl)-cyclopent-3-ene-1,3-dicarboxylate, alkenylsilanols and tricyclic aziridine derivatives. It acts as a methanogenesis inhibitor. As an electron deficient alkyne derivative, it plays a vital role in the preparation of 1,3-dienes catalyzed by rhodium(I)/H8-BINAP complex.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Ethyl 2-butynoate is used as a precursor for the synthesis of 3-ethyl, 1-methyl 1-(2-nitrophenyl)-cyclopent-3-ene-1,3-dicarboxylate, alkenylsilanols and tricyclic aziridine derivatives. It acts as a methanogenesis inhibitor. As an electron deficient alkyne derivative, it plays a vital role in the preparation of 1,3-dienes catalyzed by rhodium(I)/H8-BINAP complex.
Solubility
Miscible with water, chloroform and ethyl acetate.
Notes
Air sensitive. Incompatible with oxidizing agents, bases and acids.
RUO – Research Use Only
General References:
- Miyabe, H. Synthesis of Oxygen Heterocycles via Aromatic C-O Bond Formation Using Arynes. Molecules 2015, 20 (7), 12558-12575.
- Liu, J.; Liu, H.; Na, R.; Wang, G.; Li, Z.; Yu, H.; Wang, M.; Zhong, J.; Guo, H. Phosphine-catalyzed [3 + 2] and [3 + 3] Annulations of Azomethine Imines with Ethyl 2-Butynoate. Chem. Lett. 2012, 41 (3), 218-220.