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Thermo Scientific Chemicals
(±)-2-Methyl-2-propanesulfinamide, 97%
CAS: 146374-27-8 | C4H11NOS | 121.20 g/mol
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Catalog number B25385.03
also known as B25385-03
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Quantity:
1 g
Price (USD)
50.65
Online Exclusive
55.80Save 5.15 (9%)
Each
Chemical Identifiers
CAS146374-27-8
Specifications
Specification Sheet
Specification SheetFormPowder or crystalline powder or lumpy powder
Water Content (Karl Fischer Titration)<1.0%
Appearance (Color)White to cream to pale brown
Assay (GC)≥96.0%
(±)-2-Methyl-2-propanesulfinamide is used in the synthesis of 4-sulfonyliminopiperidine and its reaction with benzyl Grignard to form an important pharmaceutical building block, 4-benzyl-4-aminopiperidne. It is also used to prepare spiro tosylaziridines via methylene insertion into the derived sulfonylimine.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
(±)-2-Methyl-2-propanesulfinamide is used in the synthesis of 4-sulfonyliminopiperidine and its reaction with benzyl Grignard to form an important pharmaceutical building block, 4-benzyl-4-aminopiperidne. It is also used to prepare spiro tosylaziridines via methylene insertion into the derived sulfonylimine.
Solubility
Soluble in methanol.
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
(±)-2-Methyl-2-propanesulfinamide is used in the synthesis of 4-sulfonyliminopiperidine and its reaction with benzyl Grignard to form an important pharmaceutical building block, 4-benzyl-4-aminopiperidne. It is also used to prepare spiro tosylaziridines via methylene insertion into the derived sulfonylimine.
Solubility
Soluble in methanol.
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- John J.Caldwell; Ian Collins. Rapid synthesis of 4-benzyl-4-aminopiperidines by addition of Grignard reagents to N-(1-boc-piperidin-4-ylidene)-tert-butanesulfinyl imine. Synlett. 2006, (16), 2565-2568.
- Joanne Hannam; Timothy Harrison; Felicity Heath; Andrew Madin; Kevin Merchant. Rapid and selective synthesis of substituted 1,2,5-thiadiazolidine 1,1-dioxides. Synlett. 2006, (6), 833-836.