Oxoid™ Aztreonam-Avibactam Antimicrobial Susceptibility Discs

The drug aztreonam-avibactam has been designed to address infections caused by aerobic Gram-negative organisms that are resistant to other antibiotics due to the production of beta-lactamase enzymes. Aztreonam-avibactam is especially valuable for infections caused by organisms producing metallo-beta-lactamases (MBLs), which are resistant to many other beta-lactam antibiotics.

Perform susceptibility testing of multi-drug resistant aerobic Gram-negative organisms using Aztreonam-Avibactam Antimicrobial Susceptibility Discs. 

Features include:

• Meets EUCAST and CLSI recommended breakpoints
• Produces quality results in line with the rest of the Oxoid disc portfolio as demonstrated over 3 EUCAST disc quality studies
• Easy-to-use: shatterproof spring-loaded cartridges, easy-to-read labelling, and end-of-cartridge indicators
• Long-term stability ensured: each cartridge is individually sealed with a desiccant to maintain a moisture level of <2%
• Accurate and reproducible: manufactured under stringent quality standards including BS EN ISO 9001:2008, ISO 13485:2003, and FDA 21 CFR part 820, with comprehensive quality control testing
• Trusted supplier: over 35 years of experience in disc development and manufacture

Aztreonam-Avibactam has been shown to be effective against:

• Escherichia coli
• Klebsiella pneumoniae
• Klebsiella oxytoca
• Enterobacter cloacae complex
• Citrobacter freundii complex
• Serratia marcescens

Disc diffusion not only categorizes resistant, intermediate, and sensitive organisms through qualitative results but also provides a visual indication of the following:

• Inoculum level
• Presence of contamination
• Resistant mutants
• Beta-lactamase activity
• Antagonism and synergy between antibiotics

Thermo Fisher Scientific is a leader in providing AST solutions that help in the fight against antimicrobial resistance, offering high performance automated and manual test options and one of the largest, most up-to-date selections of antimicrobials for susceptibility testing.