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Zitierungen und Referenzen (31)
Invitrogen™
β-BODIPY™ FL C12-HPC (2-(4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacen-3-Dodecanoyl)-1-Hexadecanoyl-sn-Glycerin-3-Phosphocholin)
Der intensiv fluoreszierende BODIPY® (4,4-difluoro-3a,4a-diaza-s-indacene) Fluorophor ist im Gegensatz zu den meisten anderen Farbstoffen mit langer Wellenlänge intrinsisch lipophilisch. DaherWeitere Informationen
| Katalognummer | Menge |
|---|---|
| D3792 | 100 μg |
Katalognummer D3792
Preis (EUR)
245,00
Each
Menge:
100 μg
Preis (EUR)
245,00
Each
Der intensiv fluoreszierende BODIPY® (4,4-difluoro-3a,4a-diaza-s-indacene) Fluorophor ist im Gegensatz zu den meisten anderen Farbstoffen mit langer Wellenlänge intrinsisch lipophilisch. Daher ist es wahrscheinlicher, dass Sonden, die diesen Fluorophor enthalten, die Eigenschaften natürlicher Lipide nachahmen. BODIPY® Fettsäureanaloga wie BODIPY® 500/510 Dodekansäure (D-3823) und BODIPY FL Dodekansäure (D-3822) durchlaufen einen nativ-ähnlichen Transport und Stoffwechsel in Zellen. Sie sind daher wirksame Tracer für den Lipidaustausch und nützliche Allzweck-Membransonden.
Nur für Forschungszwecke. Darf nicht für diagnostische Verfahren eingesetzt werden.
Specifications
Chemischer Name oder MaterialPhospholipids
Empfohlene LagerungBei -5 bis -30 °C lagern und vor Licht schützen.
Physikalische FormFest
ProduktlinieBODIPY
Menge100 μg
Unit SizeEach
Zitierungen und Referenzen (31)
Zitierungen und Referenzen
Abstract
Separation and characterization of late endosomal membrane domains.
Journal:J Biol Chem
PubMed ID:12065580
'Very little is known about the biophysical properties and the lipid or protein composition of membrane domains presumably present in endocytic and biosynthetic organelles. Here we analyzed the membrane composition of late endosomes by suborganellar fractionation in the absence of detergent. We found that the internal membranes of this multivesicular
Multidrug transporter activity in lymphocytes.
Journal:Br J Pharmacol
PubMed ID:15492020
'Multidrug transporters play a dual role in haematopoietic cells, mediating the efflux of xenobiotics and regulating cell migration. For several reasons including the lack of specific antibodies, reports of multidrug transporter distribution on lymphocytes conflict. Murine B cells have been reported to completely lack transporter activity. Through analysis of parental
gamma-cyclodextrins greatly enhance translocation of hydrophobic fluorescent phospholipids from vesicles to cells in culture. Importance of molecular hydrophobicity in phospholipid trafficking studies.
Journal:J Biol Chem
PubMed ID:10585403
'Short-chain, fluorescent derivatives are commonly used to investigate intracellular phospholipid trafficking. However, their use can yield misleading results because they, unlike the native species, can rapidly distribute between organelles due to their low hydrophobicity. On the other hand, hydrophobic derivatives are very difficult to introduce to cells and thus have
Fluorescent membrane probes incorporating dipyrrometheneboron difluoride fluorophores.
Journal:Anal Biochem
PubMed ID:1799206
'The spectroscopic properties of a new series of fatty acid analogs in which a dipyrrometheneboron difluoride fluorophore forms a segment of the acyl methylene chain are presented and their characteristics as fluorescent membrane probes are examined. When incorporated as a low mole fraction component in model phospholipid membranes, the probes
Intracellular surfactant removal from phagocytized minerals: development of a fluorescent method using a BODIPY-labeled phospholipid.
Journal:Inhal Toxicol
PubMed ID:10880156
'Lung surfactant serves as a protective coating when adsorbed on particle surfaces, so its removal or rate of removal in vivo may affect expression of mineral cytotoxicity. Removal of phospholipid surfactant components from the surface of mineral particles ingested by alveolar macrophages (AM) was measured using fluorescence microscopy. Dipalmitoylphosphatidylcholine with