Search

  • Order Status
  • Quick Order
  • Promos
Element SearchElement SearchStructure SearchStructure Search
2,2-Difluorocyclopropanecarboxylic acid, 95%
2,2-Difluorocyclopropanecarboxylic acid, 95%
2,2-Difluorocyclopropanecarboxylic acid, 95%
Thermo Scientific Chemicals

2,2-Difluorocyclopropanecarboxylic acid, 95%

CAS: 107873-03-0 | C4H4F2O2 | 122.071 g/mol
Have Questions?
Change viewbuttonViewtableView
Quantity:
1 g
5 g
ChemDexTry the chem dexTM web app
Catalog number H25752.03
also known as H25752-03
Price (USD)
228.65
Online Exclusive
254.00
Save 25.35 (10%)
Each
Quantity:
1 g
Request bulk or custom format
Price (USD)
228.65
Online Exclusive
254.00
Save 25.35 (10%)
Each
Chemical Identifiers
CAS107873-03-0
IUPAC Name2,2-difluorocyclopropane-1-carboxylic acid
Molecular FormulaC4H4F2O2
InChI KeyKMLMOVWSQPHQME-UHFFFAOYNA-N
SMILESOC(=O)C1CC1(F)F
View more
SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White to very pale brown
FormCrystals or powder or crystalline powder
Assay (Aqueous acid-base Titration)≥94.0 to ≤106.0%
Assay (GC)≥94.0%
Melting Point (clear melt)59.0-65.0?C
2,2-Difluorocyclopropanecarboxylic acid derivative (i.e. 2,2-difluorocyclopropanecarbonyl chloride) is used in Friedel-Crafts reactions with various arenes to prepare aryl 2,2-difluorocyclopropyl ketones.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2,2-Difluorocyclopropanecarboxylic acid derivative (i.e. 2,2-difluorocyclopropanecarbonyl chloride) is used in Friedel-Crafts reactions with various arenes to prepare aryl 2,2-difluorocyclopropyl ketones.

Solubility
Soluble in water.

Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Dolbier, W. R.; Cornett, E.; Martinez, H.; Xu, W. Friedel-Crafts Reactions of 2,2-Difluorocyclopropanecarbonyl Chloride: Unexpected Ring-Opening Chemistry. J. Org. Chem. 2011, 76 (9), 3450-3456.
  2. Liu, C-H.; Wang, S-A.; Ruszczycky, M. W.; Chen, H.; Li, K.; Murakami, K.; Liu, H. Studies of 1-Amino-2,2-difluorocyclopropane-1-carboxylic Acid: Mechanism of Decomposition and Inhibition of 1-Aminocyclopropane-1-carboxylic Acid Deaminase. Org. Lett. 2015, 17 (13), 3342-3345.