Thermo Scientific Chemicals

5-(Trifluoromethyl)indole, 98%, Thermo Scientific Chemicals

Catalog number: H28782.ME
500 mg, Each
Thermo Scientific Chemicals

5-(Trifluoromethyl)indole, 98%, Thermo Scientific Chemicals

Catalog number: H28782.ME
500 mg, Each
Quantity
Catalog number: H28782.ME
also known as H28782-ME
Price (USD)
Quantity
-

Chemical Identifiers

CAS
100846-24-0
IUPAC Name
5-(trifluoromethyl)-1H-indole
Molecular Formula
C9H6F3N
InChI Key
LCFDJWUYKUPBJM-UHFFFAOYSA-N
SMILES
FC(F)(F)C1=CC=C2NC=CC2=C1
Appearance (Color)
Pale yellow to brown
Assay (GC)
≥97.5%
Melting Point (clear melt)
66.0-72.0?C
Form
Powder

Description

In 3-Naphthylindole construction by rhodium (II)-catalyzed regioselective direct arylation of indoles with 1-diazonaphthalen-2-(1H)-ones treatment of 5-(trifluoromethyl)indole(1k) or 6-(trifluoromethyl)indole (1l) with 2a afforded the desired products 3k (86%)and 3l (86%).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
In 3-Naphthylindole construction by rhodium (II)-catalyzed regioselective direct arylation of indoles with 1-diazonaphthalen-2-(1H)-ones treatment of 5-(trifluoromethyl)indole(1k) or 6-(trifluoromethyl)indole (1l) with 2a afforded the desired products 3k (86%)and 3l (86%).

Notes
Light Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, light.
RUO – Research Use Only

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