Reactant for synthesis of: TRPV1 antagonists, CHK1 inhibitors, p38a MAP kinase inhibitors, Carbamoylphosphonates, Macrolactams via carbonylation/intramolecular amidation, Intramolecular transamidation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Reactant for synthesis of: TRPV1 antagonists, CHK1 inhibitors, p38a MAP kinase inhibitors, Carbamoylphosphonates, Macrolactams via carbonylation/intramolecular amidation, Intramolecular transamidation.
Solubility
Soluble in DMSO.
Notes
Refrigerated (2-8°C). Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- Alec D. Lebsack et. Al. 1,2-Diamino-ethane-substituted-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepines as TRPV1 antagonists with improved properties. Bioorg. Med. Chem. Lett.. 2010, 20 (23),7142-7146.
- Lianyun Zhao et. al. Design, synthesis and SAR of thienopyridines as potent CHK1 inhibitors. Bioorg. Med. Chem. Lett. 2010, 20 (24),7216-7221.