Phenyl bromoacetate, 98%
Phenyl bromoacetate, 98%
Phenyl bromoacetate, 98%
Thermo Scientific Chemicals

Phenyl bromoacetate, 98%

CAS: 620-72-4 | C8H7BrO2 | 215.046 g/mol
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5 g
50 g
Catalog number H60464.06
also known as H60464-06
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36.20
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Quantity:
5 g
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Price (USD)
36.20
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Chemical Identifiers
CAS620-72-4
IUPAC Namephenyl 2-bromoacetate
Molecular FormulaC8H7BrO2
InChI KeyUEWYUCGVQMZMGY-UHFFFAOYSA-N
SMILESBrCC(=O)OC1=CC=CC=C1
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SpecificationsSpecification SheetSpecification Sheet
FormFused low-melting solid (clear liquid as melt)
Appearance (Color)White to cream or yellow to pale brown
Assay from Suppliers CofA≥97.5%
Phenyl bromoacetate may be employed as alkylation reagent in the preparation of 2-(phenoxycarbonyl)methyl triazoles. It may be used in the synthesis of the A-ring of cylindrospermopsin and in the synthesis of 2-{2-[1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)ethylidene]hydrazinyl}-1,3-thiazolidin-4-one3, 2-{2-[1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)ethylidene]hydrazinyl}-3-methyl-1,3-thiazolidin-4-one3, 3-ethyl-2-{2-[1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)ethylidene]hydrazinyl}-1,3-thiazolidin-4-one3 and 2-{2-[1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)ethylidene] hydrazinyl}-3-phenyl-1,3-thiazolidin-4-one3.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Phenyl bromoacetate may be employed as alkylation reagent in the preparation of 2-(phenoxycarbonyl)methyl triazoles. It may be used in the synthesis of the A-ring of cylindrospermopsin and in the synthesis of 2-{2-[1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)ethylidene]hydrazinyl}-1,3-thiazolidin-4-one3, 2-{2-[1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)ethylidene]hydrazinyl}-3-methyl-1,3-thiazolidin-4-one3, 3-ethyl-2-{2-[1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)ethylidene]hydrazinyl}-1,3-thiazolidin-4-one3 and 2-{2-[1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)ethylidene] hydrazinyl}-3-phenyl-1,3-thiazolidin-4-one3.

Solubility
Soluble in ethanol and ether, insoluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store under inert gas.
RUO – Research Use Only

General References:

  1. Reynold C. Fuson.; Norman. Thomas. Extension of the Reformatsky Reaction to new Types of Compounds. J. Org. Chem. 1953, 18 (12),1762-1766.
  2. Hans Thacher Clarke. XLVI.—The relation between reactivity and chemical constitution of certain halogen compounds. J. Chem. Soc., Trans. 1910, 97 416-429.