Human Plateable Hepatocytes, Induction Qualified

Catalog number: HMCPIS

Gibco™  Related applications: Hepatocytes & Hepatic Models | Primary Cell Culture

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Description

These plateable cryopreserved human hepatocytes are inducible and suitable for use in experiments monitoring in vitro enzyme induction.

Cells per vial: 4-8 million

The potentials of known clinically relevant enzyme inducers represented by 3-methylcholanthrene (3-MC, a prototypical CYP1A enzyme inducer, 3 µM), phenobarbital (PB, a prototypical CYP2B inducer, 1000 µM) and rifampicin (RIF, a prototypical CYP3A enzyme inducer, 10 µM) have been assessed to verify that each lot is inducible.

Get the Results You Need with GIBCO Hepatocytes
High quality hepatocytes, with high viabilities, in vivo-like enzyme expression levels, and proper cell morphology increase the ability to draw in vitro/in vivo correlations and make sound decisions regarding a compound's fate. Experienced technicians and proprietary isolation techniques combined with stringent release specifications ensure you receive the highest quality cryopreserved hepatocytes.

Each lot is tested for:
• Phase I and II enzyme activities
• Proper morphology
• Viabilities generally >75%
• Attachment efficiency
• Monolayer formation and integrity

For research use only. Not intended for human or animal therapeutic or diagnostic use.

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Learn more about our cryopreserved hepatocytes

Learn about our full line of hepatocytes
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Form: Cryopreserved
Species: Human
Quantity: 1 vial
Cell Type: Hepatocytes
Donor Source: Single Donor
Product Size: 1.5 mL
Number of Cells: 4-8 x 106

Contents & storage

Vials of cryopreserved hepatocytes should be stored in a cryostorage dewar or -135°C freezer.

Documents

Manuals & protocols