Methylguanidine hydrochloride can be used in the synthesis of biaryl derivatives which were evaluated as BACE1 inhibitors.
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Applications
Methylguanidine hydrochloride can be used in the synthesis of biaryl derivatives which were evaluated as BACE1 inhibitors.
Solubility
Soluble in water (50 mg/ml - clear, colorless to light yellow solution).
Notes
Hygroscopic, store away form water/moisture. Store in freezer -20°C. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent and reducing agent.
RUO – Research Use Only
General References:
- Tadashi. Inagami; Sheldon S. York. Effect of alkyl guanidines and alkyl amines on trypsin catalysis. Biochemistry, 1968, 7(11), 4045-4052.
- GuÈluÈzar Yildiz; A. Tuncay DemiryuÈrek; Inci Sahin-Erdemli; and Ilker Kanzik. Comparison of antioxidant activities of aminoguanidine, methylguanidine and guanidine by luminol-enhanced chemiluminescence. British Journal of Pharmacology, 1998 124, 905-910.