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Spironolactone
Spironolactone
Spironolactone
Thermo Scientific Chemicals

Spironolactone

CAS: 52-01-7 | C24H32O4S | 416.576 g/mol
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Catalog number J60119.03
also known as J60119-03
Price (USD)
34.60
Each
Quantity:
1 g
Request bulk or custom format
Price (USD)
34.60
Each
Chemical Identifiers
CAS52-01-7
IUPAC Name(1R,3aS,3bR,4R,9aR,9bS,11aS)-4-(acetylsulfanyl)-9a,11a-dimethyl-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydrospiro[cyclopenta[a]phenanthrene-1,2'-oxolane]-5',7-dione
Molecular FormulaC24H32O4S
InChI KeyLXMSZDCAJNLERA-ZHYRCANASA-N
SMILESCC(=O)S[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](CC[C@@]33CCC(=O)O3)[C@H]12
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SpecificationsSpecification SheetSpecification Sheet
Assay by NMRConform to structure
Loss on Drying≤0.5%
Assay (unspecified)≥ 97
FormWhite solid
Spironolactone used as potassium sparing diuretic. Also used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in chloroform and methanol. Slightly soluble in water.

Notes
Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
WARNING: Cancer – www.P65Warnings.ca.gov
RUO – Research Use Only

General References:

  1. Jakob Nielsen et. al. Sodium transporter abundance profiling in kidney: effect of spironolactone. American Journal of Physiology - Renal Physiology, 2002, 283(5), F923-F933.
  2. Femke Waanders et. al. Spironolactone ameliorates transplant vasculopathy in renal chronic transplant dysfunction in rats. American Journal of Physiology - Renal Physiology, 2009,296,(5), F1072-F1079.