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Thermo Scientific Chemicals
Carboplatin
CAS: 41575-94-4 | C6H12N2O4Pt | 371.26 g/mol
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Chemical Identifiers
CAS41575-94-4
IUPAC Name5,9-dioxo-6,8-dioxa-7-platinaspiro[3.5]nonane-7,7-bis(ylium) diamine
Molecular FormulaC6H12N2O4Pt
InChI KeyBHKICZDKIIDMNR-UHFFFAOYSA-L
SMILESN.N.O=C1O[Pt++]OC(=O)C11CCC1
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Specifications
Specification Sheet
Specification SheetAppearance (Color)White to off-white
Assay (HPLC)98.0% min.
FormPowder
Carboplatin is primarily used as an antitumor agent.Carboplatin is widely utilized as a chemotherapy drug to treat various types of cancer. It belongs to the group of platinum-based antineoplastic agents to interfere in DNA (deoxyribonucleic acid) repair. It is applied in combination other medications and used to inhibit cancer cell growth.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Soluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
RUO – Research Use Only
General References:
- Jakacki, R. I.; Burger, P. C.; Kocak, M.; Boyett, J. M.; Goldwein, J.; Mehta, M.; Packer, R. J.; Tarbell, N. J.; Pollack, I. F. Outcome and Prognostic Factors for Children With Supratentorial PrimitiveNeuroectodermal Tumors Treated With Carboplatin During Radiotherapy:A Report from the Children’s Oncology Group. Pediatr Blood Cancer 2015, 62 (5), 776-783.
- Boal, A. K.; Rosenzweig, A. C. Response from Boal and Rosenzweig to Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin. Acta Crystallogr., Sect. D: Biol. Crystallogr. 2015, 71, 1984-1986.