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Kanamycin monosulfate, Thermo Scientific Chemicals
Catalog number: J61272.22
100 g, Each
Thermo Scientific Chemicals
Kanamycin monosulfate, Thermo Scientific Chemicals
Catalog number: J61272.22
100 g, Each
Quantity
Catalog number: J61272.22
also known as J61272-22
Price (USD)
Price: 656.00
Online price: 557.65
Your price:
Quantity
-
Chemical Identifiers
CAS
25389-94-0
IUPAC Name
(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-3-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}oxane-3,4,5-triol; sulfuric acid
Molecular Formula
C18H38N4O15S
InChI Key
OOYGSFOGFJDDHP-KMCOLRRFSA-N
SMILES
OS(O)(=O)=O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
Specifications
Specification SheetOptical Rotation
+112.0 to +123° (c=1, water)
Appearance (Color)
White to cream
Form
Crystals or powder or crystalline powder
Assay from Suppliers CofA
Sulphate, SO₄: ≥15.0 to ≤17.0%
Identification (FTIR)
Conforms
Description
Antibiotic. Inhibits translocation during protein biosynthesis.Kanamycin monosulfate acts as an antibiotic and used to treat various infections. It is involved in the translation of prokaryotic ribosomes arises due to bacterial cell death. It is used as a selective agent in molecular biology in order to isolate transformants that are expressing a kanamycin resistance gene.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Kanamycin monosulfate is the sulfate salt form of kanamycin A
- It was isolated from Streptomyces kanamyceticus
- This compound inhibits translocation during protein biosynthesis. It binds to the 30S ribosomal subunit, causing misreading of the mRNA sequence
Application
- Kanamycin monosulfate shows antibacterial activity. It is effective against gram-positive and gram-negative bacteria, as well as Mycoplasma species
- This compound is also involved in translating prokaryotic ribosomes
- In molecular biology experiments, it is commonly used to select and isolate transformants expressing the kanamycin resistance gene, and plants that have the NPT II (APH3) gene incorporated
RUO – Research Use Only
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