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Streptozotocin, 97+%
Streptozotocin, 97+%
Streptozotocin, 97+%
Thermo Scientific Chemicals

Streptozotocin, 97+%

Streptozotocin (streptozocin, CAS # 18883-66-4) is an N-nitrosourea antibiotic produced by Streptomyces achromogenes. | CAS: 18883-66-4 | C8H15N3O7 | 265.222 g/mol
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Quantity:
500 mg
1 g
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Catalog number J61601.03
also known as J61601-03
Price (USD)
254.65
Special offer
Online exclusive
Ends: 28-Dec-2026
299.00
Save 44.35
Each
Quantity:
1 g
Request bulk or custom format
Price (USD)
254.65
Special offer
Online exclusive
Ends: 28-Dec-2026
299.00
Save 44.35
Each
Chemical Identifiers
CAS18883-66-4
IUPAC Name3-methyl-3-nitroso-1-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]urea
Molecular FormulaC8H15N3O7
InChI KeyZSJLQEPLLKMAKR-GKHCUFPYSA-N
SMILESCN(N=O)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O
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SpecificationsSpecification SheetSpecification Sheet
Assay (HPLC)alpha-anomer: 75.0% min.
Appearance (Color)White to pale yellow
Assay (HPLC)>97.0%
FormPowder
Streptozotocin is used to induce Type 1 diabetes for medicine.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Streptozotocin acts as a bactericidal by alkylating DNA and inhibiting DNA synthesis

• Streptozotocin enters cells through glucose transporter 2

Application

• Streptozotocin induces diabetes in experimental animals and can cause acute liver injury

• It is also useful for research on neuroendocrine tumors and carcinoma cells

WARNING: Cancer and Reproductive Harm – www.P65Warnings.ca.gov
RUO – Research Use Only

General References:

  1. Duraisamy, A.J.; Mohammad, G.; Kowluru, R.A. Mitochondrial fusion and maintenance of mitochondrial homeostasis in diabetic retinopathy. Biochim Biophys Acta Mol Basis Dis. 2019, 1865(6), 1617-1626.
  2. Zhu, Y.; Han, X.Q.; Sun, X.J.; Yang, R.; Ma, W.Q.; Liu, N.F. Lactate accelerates vascular calcification through NR4A1-regulated mitochondrial fission and BNIP3-related mitophagy. Apoptosis. 2020, (5-6), 321-340.