Cantharidin is used as a potent inhibitor of PP2A phosphatase activity. It has been shown to stimulate cell cycle progression and induce premature mitosis, used topically (0.7%) as an anti-wart treatment, and has been shown to be active in cervical, tongue, neuroblastoma, bone, leukemia, ovarian, colon, and various other cancer cell lines.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Cantharidin is used as a potent inhibitor of PP2A phosphatase activity. It has been shown to stimulate cell cycle progression and induce premature mitosis, used topically (0.7%) as an anti-wart treatment, and has been shown to be ac
RUO – Research Use Only
T I Baskin; J E Wilson. Inhibitors of protein kinases and phosphatases alter root morphology and disorganize cortical microtubules. Plant Physiology.1997, 113 , (2), 493-502.
McCluskey A.; Sim A.T.R.; and Sakoff J.A. Serine-threonine protein phosphatase inhibitors: Development of potential therapeutic strategies. J Med Chem.2002, 45 , (6), 1151-1175.