Angiotensin I (human)
Angiotensin I (human)
Angiotensin I (human)
Thermo Scientific Chemicals

Angiotensin I (human)

CAS: 484-42-4 | C62H89N17O14 | 1296.50 g/mol
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Quantity:
5 mg
25 mg
Catalog number J62102.LB0
also known as J62102-#0
Price (USD)
85.40
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Quantity:
5 mg
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Price (USD)
85.40
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Chemical Identifiers
CAS484-42-4
IUPAC Name(2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-5-[(diaminomethylidene)amino]pentanamido]-3-methylbutanamido]-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-phenylpropanamido]-3-(1H-imidazol-5-yl)propanamido]-4-methylpentanoic acid
Molecular FormulaC62H89N17O14
InChI KeyORWYRWWVDCYOMK-HBZPZAIKSA-N
SMILESCC[C@H](C)[C@H](NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC(C)C)C(O)=O
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White to off-white
FormPowder or crystals or crystalline powder
Assay≥95.0%
Mass SpecConforms
Angiotensin I (human) stimulates the release of aldosterone, another hormone, from the adrenal cortex. It acts as a precursor to angiotensin II. It acts as endogenous peptide substrate for angiotensin converting enzyme (ACE), precursor to the vasoconstrictor peptide angiotensin II

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Angiotensin I (human) stimulates the release of aldosterone, another hormone, from the adrenal cortex. It acts as a precursor to angiotensin II. It acts as endogenous peptide substrate for angiotensin converting enzyme (ACE), precursor to the vasoconstrictor peptide angiotensin II

Solubility
Soluble to 1 mg/ml in water.

Notes
Protect from heat. Incompatible with heat and oxidizing agents. Store at 4°C.
RUO – Research Use Only

General References:

  1. K Manabe; H Shirahase; H Usui; K Kurahashi and M Fujiwara. Endothelium-dependent contractions induced by angiotensin I and angiotensin II in canine cerebral artery. JPET. 1989, 251, (1), 317-320.
  2. Erdös EG; Skidgel RA. Renal metabolism of angiotensin I and II. Kidney International. Supplement. 1990, 30, S24-S27.