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Thermo Scientific Chemicals
Oxytetracycline hydrochloride
Impairs mitochondrial protein synthesis | CAS: 2058-46-0 | C22H25ClN2O9 | 496.897 g/mol
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Catalog number J62489.22
also known as J62489-22
Price (USD)
272.65
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303.00Save 30.35 (10%)
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Quantity:
100 g
Price (USD)
272.65
Online Exclusive
303.00Save 30.35 (10%)
Each
Chemical Identifiers
CAS2058-46-0
IUPAC Namehydrogen (2Z,4S,4aR,5S,5aR,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,6,10,11,12a-pentahydroxy-6-methyl-1,2,3,4,4a,5,5a,6,12,12a-decahydrotetracene-1,3,12-trione chloride
Molecular FormulaC22H25ClN2O9
InChI KeyIZRXCFCWDMSBQY-NXURVHCDSA-N
SMILES[H+].[Cl-].CN(C)[C@H]1[C@@H]2[C@@H](O)[C@H]3C(=C(O)C4=C(O)C=CC=C4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)\C(=C(\N)O)C1=O
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Specifications
Specification Sheet
Specification SheetFormPowder or crystals or crystalline powder
Loss on Drying≤2.0%
Appearance (Color)Yellow
Assay (unspecified)≥835 µg/mg (dried basis)
pH2.0-3.0
Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). Oxytetracycline hydrochloride is used to study phagosome- lysosome (P-L) fusion in P388D1 cells1 and antibiotic susceptibilities of Mycoplasma bovis isolates.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). Oxytetracycline hydrochloride is used to study phagosome- lysosome (P-L) fusion in P388D1 cells1 and antibiotic susceptibilities of Mycoplasma bovis isolates.
Solubility
Soluble in ethanol
Notes
Concentrated aqueous solutions at neutral pH will hydrolyze oxytetracycline and cause it to precipitate
Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). Oxytetracycline hydrochloride is used to study phagosome- lysosome (P-L) fusion in P388D1 cells1 and antibiotic susceptibilities of Mycoplasma bovis isolates.
Solubility
Soluble in ethanol
Notes
Concentrated aqueous solutions at neutral pH will hydrolyze oxytetracycline and cause it to precipitate
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
RUO – Research Use Only
General References:
- M Y Wells and Y Rikihisa. Lack of lysosomal fusion with phagosomes containing Ehrlichia risticii in P388D1 cells: abrogation of inhibition with oxytetracycline.. Infection and Immunity. 1988, 56, (12), 3209-3215.
- A Thomas et. al. Antibiotic susceptibilities of recent isolates of Mycoplasma bovis in Belgium. Veterinary Record. 2003, 153, (14), 428-431.