Enalaprilat
Enalaprilat
Enalaprilat
Thermo Scientific Chemicals

Enalaprilat

The active metabolite of enalapril | CAS: 76420-72-9 | C18H24N2O5 | 348.399 g/mol
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Catalog number J63392.MA
also known as J63392-MA
Price (USD)
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Ends: 30-Jun-2026
167.00
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Quantity:
10 mg
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Price (USD)
141.65
Special offer
Online exclusive
Ends: 30-Jun-2026
167.00
Save 25.35 (15%)
Each
Specifications
CAS76420-72-9
ChEBICHEBI:4786
Chemical Name or MaterialEnalaprilat
ColorWhite
EINECS Number278-459-3
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Enalapril is a ACE (angiotensin-converting enzyme) inhibitor, suggested to be more potent than Captopril (sc-200566). Studies indicate that Enalapril downregulates the expression of IL-β, IL-6, and NF-κB. Further studies show that Enalapril upregulates the expression of VEGF and heme oxygenase-1. Enalaprilat reports demonstrate that the compound has some antioxidant activity, which does not include the PKC-NADPH oxidase pathway.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Enalapril is a ACE (angiotensin-converting enzyme) inhibitor, suggested to be more potent than Captopril (sc-200566). Studies indicate that Enalapril downregulates the expression of IL-β, IL-6, and NF-κB. Further studies show that Enalapril upregulates the expression of VEGF and heme oxygenase-1. Enalaprilat reports demonstrate that the compound has some antioxidant activity, which does not include the PKC-NADPH oxidase pathway.

Solubility
Soluble in water with heating (∼60°C)

Notes
Store in a cool dry place. Keep away from oxidizing agents.
RUO – Research Use Only

General References:

  1. P. Ahlin.; J. Kristl.; A. Kristl; F. Vrečer. Investigation of polymeric nanoparticles as carriers of enalaprilat for oral administration.Int. J. Pharm. 2002, 239 (1-2),113-120 .
  2. Peter W Swaan.; Marco C Stehouwer.; Josef J Tukker. Molecular mechanism for the relative binding affinity to the intestinal peptide carrier. Comparison of three ACE-inhibitors: enalapril, enalaprilat, and lisinopril.Biochimica et Biophysica Acta (BBA) - Biomembranes. 1995, 1236 (1),31-38 .