L-Glutathione, oxidized
L-Glutathione, oxidized
L-Glutathione, oxidized
Thermo Scientific Chemicals

L-Glutathione, oxidized

Acts as hydrogen acceptor in enzymatic determination of NADP and NADPH | CAS: 27025-41-8 | C20H32N6O12S2 | 612.63 g/mol
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5 g
Catalog number J63715.06
also known as J63715-06
Price (USD)
337.65
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375.00
Save 37.35 (10%)
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Quantity:
5 g
Request bulk or custom format
Price (USD)
337.65
Online Exclusive
375.00
Save 37.35 (10%)
Each
Chemical Identifiers
CAS27025-41-8
IUPAC Name(2S)-2-amino-4-{[(1R)-2-{[(2R)-2-[(4S)-4-amino-4-carboxybutanamido]-2-[(carboxymethyl)carbamoyl]ethyl]disulfanyl}-1-[(carboxymethyl)carbamoyl]ethyl]carbamoyl}butanoic acid
Molecular FormulaC20H32N6O12S2
InChI KeyYPZRWBKMTBYPTK-IOKZUGQQNA-N
SMILESN[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O
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SpecificationsSpecification SheetSpecification Sheet
Assay (HPLC)≥98.0%
FormPowder
Water Content (Karl Fischer Titration)≤8.0%
Appearance (Color)White to pale cream
L-Glutathione is used as a Acts as hydrogen acceptor in enzymatic determination of NADP and NADPH, it is used to reduced back to glutathione (GSH) via the NADPH-dependent enzyme glutathione reductase. The ratio of GSH to GSSG is often used to gauge the level of oxidative stress in cells, with higher concentrations of GSSG implying more oxidative stress

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
L-Glutathione is used as a Acts as hydrogen acceptor in enzymatic determination of NADP and NADPH, it is used to reduced back to glutathione (GSH) via the NADPH-dependent enzyme glutathione reductase. The ratio of GSH to GSSG is often used to gauge the level of oxidative stress in cells, with higher concentrations of GSSG implying more oxidative stress

Solubility
Soluble in water, DMF, and ethanol.

Notes
Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only

General References:

  1. Nazare Pereira-Rodrigues.; Rodrigo Cofre.; Jose H. Zagal.; Fethi Bedioui. Plosker. Electrocatalytic activity of cobalt phthalocyanine CoPc adsorbed on a graphite electrode for the oxidation of reduced l-glutathione (GSH) and the reduction of its disulfide (GSSG) at physiological pH. Bioelectrochemistry. 2007, 70, (1), 147-154.
  2. Rita C.S. Luz.; Flavio S. Damos.; Auro A. Tanaka.; Lauro T. Kubota.; Yoshitaka Gushikem. Electrocatalysis of reduced l-glutathione oxidation by iron(III) tetra-(N-methyl-4-pyridyl)-porphyrin (FeT4MPyP) adsorbed on multi-walled carbon nanotubes. Talanta. 2008, 76, (5), 1097-1104.