Thermo Scientific™

G418 disulfate, 50mg/ml solution, Thermo Scientific™

50mL, Each
Thermo Scientific™

G418 disulfate, 50mg/ml solution, Thermo Scientific™

50mL, Each
Quantity
Informational:Informational:This chemical may require us to obtain additional information for our regulatory and chemical compliance records. If required, we will contact you for this information once your order is placed.
Catalog number: J63871.AD
also known as J63871-AD
Price (USD)
Price: 380.00 / Each
Your Price:
Quantity
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Chemical Identifiers

CAS
108321-42-2
IUPAC Name
5-amino-6-[(4,6-diamino-3-{[3,5-dihydroxy-5-methyl-4-(methylamino)oxan-2-yl]oxy}-2-hydroxycyclohexyl)oxy]-2-(1-hydroxyethyl)oxane-3,4-diol; bis(sulfuric acid)
Molecular Formula
C20H44N4O18S2
InChI Key
UHEPSJJJMTWUCP-UHFFFAOYNA-N
SMILES
OS(O)(=O)=O.OS(O)(=O)=O.CNC1C(O)C(OC2C(N)CC(N)C(OC3OC(C(C)O)C(O)C(O)C3N)C2O)OCC1(C)O
Appearance (Color)
Clear colorless
Absorbance
A570 nm: ≤0.10
Potency
≥700 µg/mg
Form
Liquid
Absorbance
at 280 nm: ≤0.015

Description

G418 disulfate is used for selection and maintenance of prokaryotic and eukaryotic cells transfected with a iNOS promoter construct and neomycin resistance gene. Optimal concentrations for selection and maintenance vary by cell lines.

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General description
• G418 sulfate (geneticin) is an aminoglycoside antibiotic isolated from Micromonospora rhodorangea
• G418 is bacteriostatic that prevents polypeptide formation by inhibiting the elongation step of polypeptide synthesis
Applications
• G418 sulfate can be used for the selection of genetically engineered cells in both eukaryotes and prokaryotes
• Laboratory-grade for applications such as biochemistry
RUO – Research Use Only