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Apramycin sulfate, 96%
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Apramycin sulfate, 96%
Apramycin sulfate, 96%
Apramycin sulfate, 96%
Thermo Scientific Chemicals

Apramycin sulfate, 96%

Potent inhibitor of protein synthesis in bacteria | CAS: 65710-07-8 | C21H43N5O15S | 637.66 g/mol
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Catalog number J63874.06
also known as J63874-06
Price (USD)
485.65
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539.00
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Quantity:
5 g
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Price (USD)
485.65
Online Exclusive
539.00
Save 53.35 (10%)
Each
Add to cart
Chemical Identifiers
CAS65710-07-8
IUPAC Name(2R,3R,4S,5S,6S)-2-{[(2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy}-4-hydroxy-3-(methylamino)-octahydropyrano[3,2-b]pyran-2-yl]oxy}-5-amino-6-(hydroxymethyl)oxane-3,4-diol; sulfuric acid
Molecular FormulaC21H43N5O15S
InChI KeyWGLYHYWDYPSNPF-RQFIXDHTSA-N
SMILESOS(O)(=O)=O.CN[C@H]1[C@@H](O)[C@H]2O[C@H](O[C@@H]3[C@@H](N)C[C@@H](N)[C@H](O)[C@H]3O)[C@H](N)C[C@@H]2O[C@@H]1O[C@H]1O[C@H](CO)[C@@H](N)[C@H](O)[C@H]1O
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SpecificationsSpecification SheetSpecification Sheet
FormPowder
Residue on ignition≤1.0%
Mass SpecConforms to structure
Heavy Metals≤20 ppm
Appearance (Color)Pale yellow to yellow
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This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Suitable for battery materials development.

Applications
Potent inhibitor of protein synthesis in bacteria.Apramycin sulfate is used as a potent inhibitor of protein synthesis in bacteria. It acts as an antibacterial agent. It is a useful biochemical for antibiotic and antibacterial research to study antibiotic resistance through protein synthesis inhibition by blocking translocation. It is also essential for clinic in vitro tests known as antimicrobial susceptibility tests to determine their efficacy against certain bacterial species.

Solubility
Soluble in water.

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.Incompatible with strong oxidizing agents.
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
RUO – Research Use Only

General References:

  1. Zhang, X. Y.; Ding, L. J.; Fan, M. Z. Resistance patterns and detection of aac(3)-IV gene in apramycin-resistant Escherichia coli isolated from farm animals and farm workers in northeastern of China. Res. Vet. Sci. 2009, 87 (3), 449-454.
  2. Haritova, A. M.; Djeneva, H. A.; Lashev, L. D.; Sotirova, P. G.; Gurov, B. I.; Dyankov, V. N. Pharmacokinetics of gentamicin and apramycin in turkeys roosters and hens in the context of pharmacokinetic-pharmacodynamic relationships. J. Vet. Pharmacol. Ther. 2004, 27 (5), 381-384.