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Thermo Scientific Chemicals
Penicillin G potassium salt
Inhibits bacterial cell wall synthesis | CAS: 113-98-4 | C33H36ClKN4O4S2 | 691.34 g/mol
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Catalog number J63901.14
also known as J63901-14
Price (USD)
53.20
Each
Quantity:
25 g
Price (USD)
53.20
Each
Chemical Identifiers
CAS113-98-4
IUPAC Namepotassium [3-(2-chloro-10H-phenothiazin-10-yl)propyl]dimethylamine (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Molecular FormulaC33H36ClKN4O4S2
InChI KeyHTQQVOYPSGNVPA-HBRCYENSSA-M
SMILES[K+].CN(C)CCCN1C2=CC=CC=C2SC2=CC=C(Cl)C=C12.CC1(C)S[C@@H]2[C@H](NC(=O)CC3=CC=CC=C3)C(=O)N2[C@H]1C([O-])=O
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Specifications
Specification Sheet
Specification SheetpH5.0 - 7.5, 6% in water at 25?C
Assay (unspecified)1440 - 1680 U/mg
Loss on Drying1.5% max.
Penicillin G potassium salt is used as a cell culture additive as an antibiotics. Use to inhibit the synthesis of bacterial cell walls by inhibition of the cell wall peptidoglycan chain cross-lining. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Penicillin G potassium salt is used as a cell culture additive as an antibiotics. Use to inhibit the synthesis of bacterial cell walls by inhibition of the cell wall peptidoglycan chain cross-lining. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.
Solubility
Soluble in water (100 mg/ml), methanol, ethanol (sparingly), and alcohol. Insoluble in chloroform.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Penicillin G potassium salt is used as a cell culture additive as an antibiotics. Use to inhibit the synthesis of bacterial cell walls by inhibition of the cell wall peptidoglycan chain cross-lining. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.
Solubility
Soluble in water (100 mg/ml), methanol, ethanol (sparingly), and alcohol. Insoluble in chloroform.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
RUO – Research Use Only
General References:
- Li-Li Du, Qi Wu,; Chun-Xiu Chen,; Bo-Kai Liu,; Xian-Fu Lin. A two-step, one-pot enzymatic synthesis of ampicillin from penicillin G potassium salt . Journal of Molecular Catalysis B: Enzymatic. 2009, 58 (1-4) , 208-211.
- Junhong Qian,; Rong Guo, Xia Guo. The hydrolysis of penicillin-G potassium salt in the O/W microemulsions with different charges. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2003, 215(1-3), 253-262.