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Thermo Scientific Chemicals
DAPT
CAS: 208255-80-5 | C23H26F2N2O4 | 432.468 g/mol
| Catalog Number | Quantity |
|---|---|
| J65864.MA also known as J65864-MA | 10 mg |
Catalog number J65864.MA
also known as J65864-MA
Price (USD)
223.65
Online exclusive
248.00Save 24.35
Each
Quantity:
10 mg
Price (USD)
223.65
Online exclusive
248.00Save 24.35
Each
Chemical Identifiers
CAS208255-80-5
IUPAC Nametert-butyl 2-{2-[2-(3,5-difluorophenyl)acetamido]propanamido}-2-phenylacetate
Molecular FormulaC23H26F2N2O4
InChI KeyDWJXYEABWRJFSP-UHFFFAOYNA-N
SMILESCC(NC(=O)CC1=CC(F)=CC(F)=C1)C(=O)NC(C(=O)OC(C)(C)C)C1=CC=CC=C1
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Specification SheetDAPT is used in the study of β-amyloid formation. DAPT has been shown to inhibit Notch signaling in studies of autoimmune and lymphoproliferative diseases, such as ALPS and lupus erythematosus, as well as in cancer cell growth, angiogenesis, and differentiation of human induced pluripotent stem cells.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
DAPT is used in the study of β-amyloid formation. DAPT has been shown to inhibit Notch signaling in studies of autoimmune and lymphoproliferative diseases, such as ALPS and lupus erythematosus, as well as in cancer cell growth,
DAPT is used in the study of β-amyloid formation. DAPT has been shown to inhibit Notch signaling in studies of autoimmune and lymphoproliferative diseases, such as ALPS and lupus erythematosus, as well as in cancer cell growth,
RUO – Research Use Only
General References:
- Qian Hua.; Ye Zhiwen.; Lv Chunxu. Ultrasonically promoted nitrolysis of DAPT to HMX in ionic liquid. Ultrasonics Sonochemistry. 2008, 15, (4), 326-329.
- Jayanthi, S.; Madhu, P.K.; Ramanathan, K.V. Measurement of Carbon-Proton Dipolar Couplings in Liquid Crystals Using DAPT. J. Phys. Chem. A. 2008, 112, (44), 11159-11164.