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Cefepime hydrochloride monohydrate
Cefepime hydrochloride monohydrate
Cefepime hydrochloride monohydrate
Thermo Scientific Chemicals

Cefepime hydrochloride monohydrate

Cefepime hydrochloride monohydrate, CAS # 123171-59-5, is a hydrochloride salt of the antibiotic derived from Acremonium fungus. | CAS: 123171-59-5 | C19H29Cl2N6O6S2+ | 572.497 g/mol
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Catalog number J66237.03
also known as J66237-03
Price (USD)
124.00
Each
Quantity:
1 g
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Price (USD)
124.00
Each
Chemical Identifiers
CAS123171-59-5
IUPAC Namehydrogen 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidin-1-ium hydrate dichloride
Molecular FormulaC19H28Cl2N6O6S2
InChI KeyLRAJHPGSGBRUJN-OMIVUECESA-N
SMILES[H+].O.[Cl-].[Cl-].CON=C(/C(=O)N[C@H]1[C@H]2SCC(C[N+]3(C)CCCC3)=C(N2C1=O)C(O)=O)C1=CSC(N)=N1
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SpecificationsSpecification SheetSpecification Sheet
FormPowder
Appearance (Color)White to pale yellow
Assay (HPLC)84.0 - 90.0 %, as cefepime
Water Content (Karl Fischer Titration)3.0 - 6.0%
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Suitable for battery materials development.

General Description

• Cefepime hydrochloride is a fourth-generation cephalosporin antibiotic that works against most antibiotic resistant strains of bacteria

• Cefepime hydrochloride is a penicillin binding protein inhibitor that prevents peptidoglycan cross-linkage and leads to cell wall weakening and lysis

Application

• Cefepime hydrochloride monohydrate can be used for the laboratory study of microbial physiology and antibiotic resistance

• Cefepime has broad-spectrum activity; it is appropriate for research on bacteria responsible for resistant infections and physiological studies

RUO – Research Use Only

General References:

  1. Pilmis B, Mizrahi A, Petitjean G, Le Monnier A, El Helali N. Clinical evaluation of subcutaneous administration of cefepime. Med Mal Infect. 2020 May;50(3):308-310. doi: 10.1016/j.medmal.2019.12.006. Epub 2020 Jan 7. PMID: 31924455.
  2. Rodvold KA, Gotfried MH, Chugh R, Gupta M, Patel A, Chavan R, Yeole R, Friedland HD, Bhatia A. Plasma and Intrapulmonary Concentrations of Cefepime and Zidebactam following Intravenous Administration of WCK 5222 to Healthy Adult Subjects. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e00682-18. doi: 10.1128/AAC.00682-18. PMID: 29784852; PMCID: PMC6105785.