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Anisomycin, 10 mg/ml in DMSO, sterile-filtered
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Anisomycin, 10 mg/ml in DMSO, sterile-filtered
Anisomycin, 10 mg/ml in DMSO, sterile-filtered
Anisomycin, 10 mg/ml in DMSO, sterile-filtered
Thermo Scientific Chemicals

Anisomycin, 10 mg/ml in DMSO, sterile-filtered

CAS: 22862-76-6 | C14H19NO4 | 265.31 g/mol
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Catalog NumberQuantity
J67498.XF
also known as J67498-XF
1 mL
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Catalog number J67498.XF
also known as J67498-XF
Price (USD)
253.00
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Quantity:
1 mL
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Price (USD)
253.00
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Chemical Identifiers
CAS22862-76-6
IUPAC Name(2S,3R,4R)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl acetate
Molecular FormulaC14H19NO4
InChI KeyYKJYKKNCCRKFSL-BFHYXJOUSA-N
SMILESCOC1=CC=C(C[C@@H]2NC[C@@H](O)[C@@H]2OC(C)=O)C=C1
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SpecificationsSpecification SheetSpecification Sheet
FormLiquid
CompositionAnisomycin: 10 mg/mL in DMSO, sterile filtered
It is applied as an antiparasitic agent and antineoplastic agent. It acts as a protein synthesis inhibitor (blocks translation), potent activator of stress-activated protein kinases (JNK/SAPK) and p38 MAP kinase. It also scts as a potent signaling agonist to selectively elicit homologous desensitization of immediate early gene induction (c-fos, fosB, c-jun, junB and junD). Activates mitogen-activated protein (MAP) kinases (JNK/SAPK and p38/RK).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is applied as an antiparasitic agent and antineoplastic agent. It acts as a protein synthesis inhibitor (blocks translation), potent activator of stress-activated protein kinases (JNK/SAPK) and p38 MAP kinase. It also scts as a p
RUO – Research Use Only

General References:

  1. Cano E, et al. Anisomycin-activated protein kinases p45 and p55 but not mitogen-activated protein kinases ERK-1 and -2 are implicated in the induction of c-fos and c-jun.Mol Cell Biol.,1994,14,(11), 7352-62.
  2. Grollman, A.P. Inhibitors of protein biosynthesis.J Biol Chem.,1967,242,(13), 3226-3233.