Tango™ H4-bla U2OS

Catalog number: K1465

 Related applications: Pharma & Biopharma | Target & Lead Identification & Validation

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The Tango™ H4-bla U2OS cells contain the human Histamine Receptor 4 (H4) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The Tango™ H4-bla U2OS cells are functionally validated for Z' and EC50 concentrations of 4-Methylhistamine. In addition, Tango™ H4-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.
For Research Use Only. Not for use in diagnostic procedures.


System: Tango™
Readout: End Point
Reporter: BLA (Beta-Lactamase)
Cell Line: U2OS
Technique: FRET
Cell State: Division-Arrested Cells
Gene Symbol: HRH4
Product Size: 8 x 106 cells
Accession Number: NP_067637.2
Cytoplasmic Tail: Tail from AVPR2 GPCR
Detection Method: Fluorescent
Druggable Target: GPCRs
Population Status: Single Cell Clone Origin

Contents & storage

K1465 Tango™ H4-bla U2OS cells
(LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
• Tango™ H4-bla U2OS cells
• Tango™ H4-bla U2OS Assay Protocol
• Certificate of Analysis

The Tango™ H4-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.


Manuals & protocols