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Thermo Scientific™

GeneBLAzer™ ADRB2-CRE-bla CHO-K1 Cells

Catalog number:  K1472

Related applications:

Pharma & Biopharma

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Description

The GeneBLAzer® ADRB2-CRE-bla CHO-K1 cells contain the human Adrenergic Beta-2 Receptor (ADRB2), (Accession # NM_000024.3) stably integrated into the CellSensor® CRE-bla CHO-K1 cell line. CellSensor® CRE-bla CHO-K1 cells (Cat # K1129) contain a beta-lactamase (bla) reporter gene under control of the cAMP response element (CRE).

The ADRB2-CRE-bla CHO-K1 cells are functionally validated for Z'-factor and EC50 concentrations of Isoproterenol. In addition, ADRB2-CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NM_000024.3
Assay Entry: Cell-based beta lactamase reporter gene
Cell Line: CHO-K1
Cell State: Dividing Cells
Detection Method: Fluorescent
Druggable Target: GPCRs
Gene Symbol: ADRB2
Population Status: Single Cell Clone Origin
Product Line: GeneBLAzer®
Reporter Gene: BLA (Beta-Lactamase)
System Type: GeneBLAzer™
Target Entry: ADRB2

Contents & storage

(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
o GeneBLAzer® ADRB2-CRE-bla CHO-K1 cells
o GeneBLAzer® ADRB2-CRE-bla CHO-K1 Assay Protocol
o Certificate of Analysis
The GeneBLAzer® ADRB2-CRE-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.