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Thermo Scientific™

GeneBLAzer™ ADORA2A-CRE-bla CHO-K1 Cells

Catalog number: K1530
Thermo Scientific™

GeneBLAzer™ ADORA2A-CRE-bla CHO-K1 Cells

Catalog number: K1530
Catalog Number
K1530
Unit Size
2 x 106 cells
Price (USD)
8,140.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
K15302 x 106 cells
8,140.00
Your Price:
***
Product Overview
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GeneBLAzer® ADORA2A-CRE-bla CHO-K1 cells contain the human Adenosine Receptor A2A (ADORA2A) stably integrated into the CellSensor® CRE-bla CHO-K1 cell line. CellSensor® CRE-bla CHO-K1 cells (Cat. no. K1535) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.

The GeneBLAzer® ADORA2A-CRE-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of NECA. In addition, GeneBLAzer® ADORA2A-CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

ADORA2A has been shown to have many roles throughout the body. ADORA2A is involved in pain and inflammation regulation, inhibition of platelet aggregation, blood pressure regulation and contributes to ischemic brain damage. Selective antagonists of the ADORA2A pathway are being tested as adjuvants to dopaminergic drugs to treat Parkinson's disease and schizophrenia.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

Specifications

Accession Number
NM_000675
Assay Entry
Cell-based beta lactamase reporter gene
Cell State
Dividing Cells
Detection Method
Fluorescent
For Use With (Application)
FRET
Gene Symbol
ADORA2A
Population Status
Single Cell Clone Origin
Product Line
GeneBLAzer™
Reporter Gene
BLA (Beta-Lactamase)
Target Entry
ADORA2A
Cell Line
CHO-K1
System Type
GeneBLAzer™
Druggable Target
GPCRs

Contents & Storage

Contents:
K1530 GeneBLAzer™ ADORA2A-CRE-bla CHO-K1 cells
(LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• GeneBLAzer™ ADORA2A-CRE-bla CHO-K1 cells
• GeneBLAzer™ ADORA2A-CRE-bla CHO-K1
• Certificate of Analysis

Storage:
The GeneBLAzer™ ADORA2A-CRE-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

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