CellSensor™ AP-1-bla ME-180 Cell Line
Product Images
Invitrogen™
CellSensor™ AP-1-bla ME-180 Cell Line
The CellSensor® AP-1-bla ME-180 Cell Line contains a beta-lactamase reporter gene under control of the AP-1 response element stably integratedRead more
Have Questions?
Catalog number K1661
Price (USD)/ 1 vial
10,580.00
-
Add to cart
Price (USD)/ 1 vial
10,580.00
Add to cart
CellSensor™ AP-1-bla ME-180 Cell Line
Catalog numberK1661
Price (USD)/ 1 vial
10,580.00
-
Add to cart
The CellSensor® AP-1-bla ME-180 Cell Line contains a beta-lactamase reporter gene under control of the AP-1 response element stably integrated into ME-180 cells. The cell line was created through FACS sorting of cells responsive to stimulation of the AP-1 pathway with Epidermal Growth Factor (EGF). This cell line was validated for DMSO tolerance, stimulant incubation time, substrate loading conditions, Z' and EC50 concentration of Epidermal Growth Factor. The AP-1-bla ME-180 Cell Line responds to agonist treatment as expected from the literature and can be adapted for high-throughput screening for agonists or antagonists of the AP-1 pathway with compound libraries. Candidate drugs can also be tested for dose response against this cell line. Academic and non-profit customers, please inquire for special pricing.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Assay EntryCell-based beta lactamase reporter gene
Cell StateDividing Cells
Product LineCellSensor™
Quantity1 vial
Target EntryEGFR, ERK1/2, p38, MEK, MAPK pathway, c-MET, JNK, RON, RAF
TypeCell Line
Cell LineME-180
System TypeCellSensor™
Druggable TargetSignaling Pathway
Unit Size1 vial
Contents & Storage
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.