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Thermo Scientific™

GeneBLAzer™ ERβ-UAS-bla GripTite™ Cells

Catalog number: K1689B
Thermo Scientific™

GeneBLAzer™ ERβ-UAS-bla GripTite™ Cells

Catalog number: K1689B
Catalog Number
K1689B
Unit Size
2 x 106 cells
Price (USD)
8,140.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
K1689B2 x 106 cells
8,140.00
Your Price:
***
Product Overview
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ER beta-UAS-bla GripTite™ 293 cells contain the ligand-binding domain (LBD) of the human Estrogen receptor beta (ER beta) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer®UAS-bla GripTite™ 293 cell line. GeneBLAzer®UAS-bla GripTite™ 293 cells stably express a betalactamase reporter gene under the transcriptional control of an upstream activator sequence (UAS). When an agonist binds to the LBD of the GAL4 (DBD)-ER beta (LBD) fusion protein, the protein binds to the UAS, resulting in expression of beta-lactamase. Division Arrested (DA) cells are available in two configurations- an Assay Kit (which includes cells and sufficient substrate to analyze 1 x 384-well plate), and a tube of cells sufficient to analyze 10 x 384-well plates. ER beta-UAS-bla GripTite™293 cells are functionally validated for Z' and EC50 concentrations of 17-beta Estradiol. In addition, ER beta-UAS-bla GripTite™293 cells have been tested for assay performance under variable conditions, including DMSO concentration, cell number, stimulation time, and substrate loading time. Additional testing data using alternate stimuli are also available.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Cell State
Dividing Cells
Detection Method
Fluorescent
Druggable Target
Nuclear Receptors
Reporter Gene
BLA (Beta-Lactamase)
Shipping Condition
Room Temperature
System Type
GeneBLAzer™
Type
GripTite Cells

Contents & Storage

Shipping: Dry IceStorage: -80°C/Liquid NitrogenContains: ER beta-UAS-bla GriptTite™ cells (K1091)

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