GeneBLAzer™ H1-NFAT-bla HEK293T cells contain the human Histamine Receptor 1 (H1) stably integrated into the CellSensor™ NFAT-bla HEK293T cell line. CellSensor™ NFAT-bla HEK293T cells (Cat. no. K1538) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.
The GeneBLAzer™ H1-NFAT-bla HEK293T cells are functionally validated for Z' and EC50 concentrations Histamine. In addition, GeneBLAzer™ H1-NFAT-bla HEK293T cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
The H1 receptor is located in human bronchi, bronchioles, and bronchial muscle, smooth muscle of the ileum, and the uterus. H1 receptors play a role in various disorders, including allergic reactions and mood disorders.
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For Research Use Only. Not for use in diagnostic procedures.