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GeneBLAzer® H2-CRE-bla HEK293T cells contain the human Histamine Receptor 2 (H2) stably integrated into the CellSensor® CRE-bla HEK293T cell line. CellSensor® CRE-bla HEK293T cells (Cat. no. K1540) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.
The GeneBLAzer® H2-CRE-bla HEK293T cells are functionally validated for Z' and EC50 concentrations of Histamine. In addition, GeneBLAzer® H2-CRE-bla HEK293T cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
The H2 receptor has been implicated in a number of disorders, including peptic ulcer disease (PUD), gastroesophageal reflux disease (GERD), dyspepsia, and stress ulcer prophylaxis.
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For Research Use Only. Not for use in diagnostic procedures.
Cell-based beta lactamase reporter gene
For Use With (Application)
Single Cell Clone Origin
Contents & Storage
Contents: K1707 GeneBLAzer™ H2-CRE-bla HEK293T cells (LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol). Includes: • GeneBLAzer™ H2-CRE-bla HEK293T cells • GeneBLAzer™ H2-CRE-bla HEK293T Assay Protocol • Certificate of Analysis
Storage: The GeneBLAzer™ H2-CRE-bla HEK293T cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.