Thermo Scientific™

GeneBLAzer™ MC5R-CRE-bla CHO-K1 Cells

Catalog number: K1740
Thermo Scientific™

GeneBLAzer™ MC5R-CRE-bla CHO-K1 Cells

Catalog number: K1740
Catalog Number
K1740
Unit Size
2 × 10^6 cells
Price (USD)
Price: 9,100.00
Your Price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
K17402 × 10^6 cells
Price: 9,100.00
Your Price:
-
Product Overview
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GeneBLAzer™ MC5R-CRE-bla CHO-K1 cells contain the human Melanocortin Receptor 5 (MC5R) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line. CellSensor™ CRE-bla CHO-K1 cells (Cat. no. K1535) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.

The GeneBLAzer™ MC5R-CRE-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of NPD-α MSH In addition, GeneBLAzer™ MC5R-CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

MC5R is expressed in skin, muscle, lung, liver, spleen, and adrenal tissue. MC5R is Gs-coupled and binds all of the melanocortin peptides and ACTH. A recent study suggests that MC5R is involved in fat storage in the sebocyte cells of the skin. Another study in mice links MC5R to aggressive behavior. Mice deficient in MC5R acted less aggressively when treated with alpha-MSH.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NM_005913.1
Assay Entry
Cell-based beta lactamase reporter gene
Cell State
Dividing Cells
Detection Method
Fluorescent
For Use With (Application)
FRET
Gene Symbol
MC5R
Population Status
Single Cell Clone Origin
Product Line
GeneBLAzer™
Reporter Gene
BLA (Beta-Lactamase)
Target Entry
MC5R
Cell Line
CHO-K1
System Type
GeneBLAzer™
Druggable Target
GPCRs

Contents & Storage

Contents:
K1740 GeneBLAzer™ MC5R-CRE-bla CHO-K1 cells
(LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• GeneBLAzer™ MC5R-CRE-bla CHO-K1 cells
• GeneBLAzer™ MC5R-CRE-bla CHO-K1 Assay Protocol
• Certificate of Analysis

Storage:
The GeneBLAzer™ MC5R-CRE-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.