GeneBLAzer® NTSR1 CHO-K1 DA Assay Kit

Catalog number: K1773

 Related applications: Target & Lead Identification & Validation

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Description

The GeneBLAzer® NTSR1 CHO-K1 DA cells contain the human Neurotensin Receptor 1 (NTSR1) stably integrated into the GeneBLAzer® Gqo5-NFAT-bla CHO-K1 cell line. CellSensor® NFAT-bla CHO-K1 cells (Cat. no. K1078) contain a beta-lactamase reporter gene under control of the NFAT response element.

The GeneBLAzer® NTSR1 CHO-K1 DA cells have been functionally validated for Z' factor and EC50 concentrations of established ligands. In addition, GeneBLAzer® NTSR1 CHO-K1 DA cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary for each product. Division Arrested cells are irreversibly division arrested using a low-dose treatment of Mitomycin C, and have no apparent toxicity or change in cellular signal transduction.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

System: GeneBLAzer®
Readout: End Point
Reporter: BLA (Beta-Lactamase)
Cell Line: U2OS
Cell State: Division-Arrested Cells
Gene Symbol: NTSR1
Product Size: 1 kit
Protein Family: GPCR (G-Protein Coupled Receptors)
Accession Number: NM_002531
Detection Method: Fluorescent
Druggable Target: GPCRs
Population Status: Pool of Stable Cells

Contents & storage

K1773 GeneBLAzer® NTSR1 CHO-K1 DA Assay Kit
(LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• GeneBLAzer® NTSR1 CHO-K1 DA cells
• LiveBLAzer™-FRET B⁄G Loading Kit, 70µg
• Solution D
• GeneBLAzer® NTSR1 CHO-K1 DA Assay Protocol
• LiveBLAzer™-FRET B⁄G Loading Protocol
• Certificate of Analysis
The GeneBLAzer® NTSR1 CHO-K1 DA cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Documents

Manuals & protocols