Thermo Scientific™

Tango™ HTR1A-bla U2OS Cells

Catalog number: K1857
Thermo Scientific™

Tango™ HTR1A-bla U2OS Cells

Catalog number: K1857
Catalog Number
K1857
Unit Size
8 x 106 cells
Price (USD)
Price: 9,190.00
Your Price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
K18578 x 106 cells
Price: 9,190.00
Your Price:
-
Product Overview
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Tango™ HTR1A-bla U2OS cells contain the human Serotonin Type 1a receptor (HTR1A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin⁄TEV protease fusion protein and the beta-lactamase reporter gene under the control of a UAS response element. Tango™ HTR1A-bla U2OS DA cells have been functionally validated for Z’ factor and EC50 concentrations of 5-CT (Figure 1). In addition, Tango™ HTR1A-bla U2OS cells have been tested for assay performance under variable conditions.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NM_000524
Assay Entry
Cell-based beta-arrestin recruitment
Cell State
Dividing Cells
Cytoplasmic Tail
Tail from AVPR2 GPCR
Detection Method
Fluorescent
For Use With (Application)
FRET
Gene Symbol
HTR1A
Human Protein Class
G-Protein Coupled Receptor (GPCR)
Population Status
Single Cell Clone Origin
Product Line
Tango™
Readout
End Point
Target Entry
5HT1A, HTR1A
Cell Line
U2OS
System Type
Tango™
Druggable Target
GPCRs

Contents & Storage

K1857 Tango™ HTR1A-UAS-bla CHO-K1 cells
(LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• Tango™ HTR1A-UAS-bla CHO-K1 cells
• Tango™ HTR1A-UAS-bla CHO-K1 Assay Protocol
• Certificate of Analysis
The Tango™ HTR1A-UAS-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.