Effects of prenatal stress exposure on soluble Aß and brain-derived neurotrophic factor signaling in male and female APPswe/PS1dE9 mice.
AuthorsSierksma AS, Vanmierlo T, De Vry J, Raijmakers ME, Steinbusch HW, van den Hove DL, Prickaerts J,
JournalNeurochem Int
PubMed ID22750275
Chronic stress and stress-related disorders, such as major depression (MD), have been shown to increase the risk for developing Alzheimer's disease (AD). Brain-derived neurotrophic factor (BDNF) has been postulated as a neurophysiological link between these illnesses. Our previous research has indicated that exposing the APPswe/PS1dE9 mouse model of AD to ... More