2,6-Diisopropylaniline, 90+%
2,6-Diisopropylaniline, 90+%
2,6-Diisopropylaniline, 90+%
2,6-Diisopropylaniline, 90+%
Thermo Scientific Chemicals

2,6-Diisopropylaniline, 90+%

CAS: 24544-04-5 | C12H19N | 177.291 g/mol
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Catalog number L10761.36
also known as L10761-36
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500 g
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Price (USD)
88.65
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Online exclusive
Ends: 30-Jun-2026
104.00
Save 15.35 (15%)
Each
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Chemical Identifiers
CAS24544-04-5
IUPAC Name2,6-bis(propan-2-yl)aniline
Molecular FormulaC12H19N
InChI KeyWKBALTUBRZPIPZ-UHFFFAOYSA-N
SMILESCC(C)C1=CC=CC(C(C)C)=C1N
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SpecificationsSpecification SheetSpecification Sheet
Assay (GC)≥90.0%
Identification (FTIR)Conforms
Refractive Index1.4930-1.5730 @ 20?C
FormLiquid
Appearance (Color)Clear colorless to yellow to orange to red to brown
2,6-Diisopropylaniline acts as an intermediate used in the production of carbodiimides stabilizers, synthetic resins, antioxidants and active pharmaceutical ingredients. It is also used in the preparation of multitopic Schiff-base ligand precursors and 4,5-bis(2,6-diisopropylanilino)-2,7-di-tert-butyl-9,9-dimethylthioxanthene. It also undergoes condensation reaction with triacetylmethane to get -[1-(2,6-diisopropylphenylamino)ethylidene]pentane-2,4-dione. Further, it is used to prepare N-heterocyclic carbene complexes for alfa-arylation of acyclic ketones, amination of haloarenes and aqueous Suzuki coupling. In addition to this, it is used in the prepartion of organocatalyst based on naphthalene diimides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2,6-Diisopropylaniline acts as an intermediate used in the production of carbodiimides stabilizers, synthetic resins, antioxidants and active pharmaceutical ingredients. It is also used in the preparation of multitopic Schiff-base ligand precursors and 4,5-bis(2,6-diisopropylanilino)-2,7-di-tert-butyl-9,9-dimethylthioxanthene. It also undergoes condensation reaction with triacetylmethane to get -[1-(2,6-diisopropylphenylamino)ethylidene]pentane-2,4-dione. Further, it is used to prepare N-heterocyclic carbene complexes for alfa-arylation of acyclic ketones, amination of haloarenes and aqueous Suzuki coupling. In addition to this, it is used in the prepartion of organocatalyst based on naphthalene diimides.

Solubility
Miscible with ether and alcohol. Slightly miscible with water.

Notes
Incompatible with acids, acid chlorides, acid anhydrides, chloroformates and strong oxidizing agents.
RUO – Research Use Only

General References:

  1. This hindered amine has been converted to the nitrile in 52% yield by treatment with alkyl nitrite and copper(I) cyanide in DMSO, as an alternative to the classical Sandmeyer conditions: Tetrahedron, 52, 7137 (1996).
  2. Dyar, S. M.; Smeigh, A. L.; Karlen, S. D.; Young, R. M.; Wasielewski, M. R. Photo-initiated multi-step electron transfer in donor-acceptor systems using a novel bi-functionalized perylene chromophore. Chem. Phys. Lett. 2015, 629, 23-28.
  3. Guo, Z.; Wei, X.; Hua, Y.; Chao, J.; Liu, D. Synthesis of 2-benzoylpyrrole derivatives via C-H functionalization adjacent to nitrogen of pyrrole. Tetrahedron Lett. 2015, 56 (25), 3919-3922.