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Thermo Scientific Chemicals
3-Hydroxy-1-methylpiperidine, 98%, Thermo Scientific Chemicals
| Catalog Number | Quantity |
|---|---|
| L10829.06 also known as L10829-06 | 5 g |
Chemical Identifiers
CAS3554-74-3
IUPAC Name1-methylpiperidin-3-ol
Molecular FormulaC6H13NO
InChI KeyUKANCZCEGQDKGF-UHFFFAOYNA-N
SMILESCN1CCCC(O)C1
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Specifications
Specification Sheet
Specification SheetFormLiquid or viscous liquid
Appearance (Color)Clear colorless to orange
Assay (GC)≥97.5%
Refractive Index1.4720-1.4760 @ 20?C
Reactant for Optimization of Novobiocin scaffold to produce antitumor agents, Formation of carbamates and N-alkylimidazoles. Reactant for synthesis of Pyridine derivatives as CDK5 inhibitors Phenylcarbamate derivatives as ligands for nicotinic acetylcholine receptors, Amino phosphite ligands, Mexiletine enantiomers by nucleophilic aromatic substitution.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Reactant for Optimization of Novobiocin scaffold to produce antitumor agents, Formation of carbamates and N-alkylimidazoles. Reactant for synthesis of Pyridine derivatives as CDK5 inhibitors Phenylcarbamate derivatives as ligands for nicotinic acetylcholine receptors, Amino phosphite ligands, Mexiletine enantiomers by nucleophilic aromatic substitution.
Solubility
Fully misicible in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
Reactant for Optimization of Novobiocin scaffold to produce antitumor agents, Formation of carbamates and N-alkylimidazoles. Reactant for synthesis of Pyridine derivatives as CDK5 inhibitors Phenylcarbamate derivatives as ligands for nicotinic acetylcholine receptors, Amino phosphite ligands, Mexiletine enantiomers by nucleophilic aromatic substitution.
Solubility
Fully misicible in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
RUO – Research Use Only
General References:
- Huiping Zhao et. al. Engineering an antibiotic to fight cancer: optimization of the novobiocin scaffold to produce anti-proliferative agents.. Journal of medicinal and pharmaceutical chemistry,. 2007, 54 (11), 3839-3853.
- Matthew R. Kaller et. al. Design and synthesis of 6-oxo-1,6-dihydropyridines as CDK5 inhibitors. Bioorganic & Medicinal Chemistry Letters. 2009, 19 (23), 6591-6594.
- The Na derivative can be used in combination with Ni(OAc) 2 aH for desufurization of thioethers, showing dramatic rate enhancement compared with other systems: Tetrahedron Lett ., 39, 8987 (1998).