Ethyl 2-nitropropionate, 96%
Ethyl 2-nitropropionate, 96%
Ethyl 2-nitropropionate, 96%
Thermo Scientific Chemicals

Ethyl 2-nitropropionate, 96%

CAS: 2531-80-8 | C5H9NO4 | 147.13 g/mol
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1 g
5 g
Catalog number L12261.03
also known as L12261-03
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Quantity:
1 g
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Price (USD)
26.65
Special offer
Online exclusive
Ends: 30-Jun-2026
30.90
Save 4.25 (14%)
Each
Chemical Identifiers
CAS2531-80-8
SpecificationsSpecification SheetSpecification Sheet
FormLiquid
Assay (GC)≥95.0%
Refractive Index1.4185-1.4245 @ 20?C
Appearance (Color)Clear colorless to pale yellow
Ethyl 2-nitropropionate is used in the preparation of (-)-trans-2,5-dimethylprolineethyl ester via enantioselective Michael reaction methyl vinyl ketone using modified dihydroquinine as catalyst, novel nitrogen-15-labeled nitrone spin trap, 5-ethoxycarbonyl-5-methyl-1-pyrroline N-oxide ([15N]EMPO) for detecting superoxide anion, 2-ethoxycarbonyl-2-nitropentanal. It is used for enantioselective Michael reactions.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ethyl 2-nitropropionate is used in the preparation of (-)-trans-2,5-dimethylprolineethyl ester via enantioselective Michael reaction methyl vinyl ketone using modified dihydroquinine as catalyst, novel nitrogen-15-labeled nitrone spin trap, 5-ethoxycarbonyl-5-methyl-1-pyrroline N-oxide ([15N]EMPO) for detecting superoxide anion, 2-ethoxycarbonyl-2-nitropentanal. It is used for enantioselective Michael reactions.

Solubility
Not miscible in water.

Notes
Incompatible with oxidizing agents. Store in a cool, dry conditions in well sealed container.
RUO – Research Use Only

General References:

  1. Jeremy R Duvall; Fanghui Wu; Barry B Snider. Structure reassignment and synthesis of Jenamidines A1/A2, synthesis of (+)-NP25302, and formal synthesis of SB-311009 analogues. J. Org. Chem.2006, 71, (22), 8579-8590.
  2. H Zhang; J Joseph; J Vasquez-Vivar; H Karoui; C Nsanzumuhire; P Martásek; P Tordo; B Kalyanaraman. FEBS Letters.2000, 473, (1), 58-62.