O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate, 99%
O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate, 99%
O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate, 99%
Thermo Scientific Chemicals

O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate, 99%

CAS: 125700-67-6 | C11H16BF4N5O | 321.09 g/mol
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Catalog number L13470.03
also known as L13470-03
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Chemical Identifiers
CAS125700-67-6
IUPAC Name[(1H-1,2,3-benzotriazol-1-yloxy)(dimethylamino)methylidene]dimethylazanium; tetrafluoroboranuide
Molecular FormulaC11H16BF4N5O
InChI KeyJKEKMBGUVUKMQB-UHFFFAOYSA-N
SMILESF[B-](F)(F)F.CN(C)C(ON1N=NC2=CC=CC=C12)=[N+](C)C
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SpecificationsSpecification SheetSpecification Sheet
Loss on Drying≤1.0%
FormCrystalline powder or powder
Appearance (Color)White to cream
Assay (HPLC)≥98.5%
O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate is used as used for solid-phase peptide synthesis. It is also used to study ten different phosphonium and uronium salt-based coupling reagents, which are used to synthesize four peptides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
O-(1H-Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate is used as used for solid-phase peptide synthesis. It is also used to study ten different phosphonium and uronium salt-based coupling reagents, which are used to synthesize four peptides.

Solubility
Soluble in acetonitrile (100 mg/ml, clear, colorless), DMF (160.55 mg/ml, clear), and water (3 mg/ml at 20°C).

Notes
Incompatible with oxidizing agents. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature is 2-8°C. Sensitive to light and moisture. Store under inert gas.
RUO – Research Use Only
Iman Abdelmoty.; Fernando Albericio.; Louis A. Carpino.; Bruce M. Foxman.; Steven A. Kates. Structural studies of reagents for peptide bond formation: Crystal and molecular structures of HBTU and HATU. Letters in Peptide Science. 1986, 94 (1), 57-67.